FB2026_02 , released June 18, 2026
Allele: Dmel\Rev1DTD
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General Information
Symbol
Dmel\Rev1DTD
Species
D. melanogaster
Name
FlyBase ID
FBal0404841
Feature type
allele
Associated gene
Dmel\Rev1
Associated Insertion(s)
TI{TI}Rev1DTD
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Khodaverdian et al., 2024)
Mutagen
I-CreI
(Khodaverdian et al., 2024)
phiC31 integrase
(Khodaverdian et al., 2024)
recombination
(Khodaverdian et al., 2024)
Progenitor genotype
Associated Insertion(s)
TI{TI}Rev1DTD
Cytology
Description

Amino acid replacement: D421A.

(Khodaverdian et al., 2024)

Endogenous Rev1 in which the D421A and G422A mutations have been introduced; created via the SIRT (site-specific integrase mediated repeated targeting) technique.

(Khodaverdian et al., 2024)

Amino acid replacement: G422A.

(Khodaverdian et al., 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      PolZ13B, Rev1DTD has chemical sensitive phenotype

      (Khodaverdian et al., 2024)

      PolZ13B, Rev1DTD has increased mortality | chemical conditional phenotype

      (Khodaverdian et al., 2024)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rev1-DTD
      (Khodaverdian et al., 2024)
      Rev1DTD
      Name Synonyms
      Secondary FlyBase IDs
        References (1)