FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Alkbh81-IC
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General Information
Symbol
Dmel\Alkbh81-IC
Species
D. melanogaster
Name
FlyBase ID
FBal0406439
Feature type
allele
Associated gene
Dmel\Alkbh8
Associated Insertion(s)
TI{TI}Alkbh81-IC
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Madhwani et al., 2024)
Mutagen
CRISPR/Cas9
(Madhwani et al., 2024)
Progenitor genotype
Associated Insertion(s)
TI{TI}Alkbh81-IC
Cytology
Description

An interfering cassette encoding a visible marker flanked by piggyBac inverted repeat sequences is inserted immediately downstream of the Alkbh8 translation start.

(Madhwani et al., 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
2R:22,635,921..22,635,922 [-]
Comment:

An interfering cassette encoding a visible marker flanked by piggyBac inverted repeat sequences is inserted immediately downstream of the Alkbh8 translation start.

(Madhwani et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      Alkbh81-IC has NMJ bouton | larval stage | increased number phenotype, non-enhanceable by Sps2EY00228

      (Madhwani et al., 2024)
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Alkbh81-IC has NMJ bouton | increased number | larval stage phenotype, non-suppressible by Sps2EY00228

      (Madhwani et al., 2024)
      NOT Enhancer of
      Statement
      Reference

      Alkbh81-IC is a non-enhancer of NMJ bouton | larval stage | increased number phenotype of Sps2EY00228

      (Madhwani et al., 2024)
      NOT Suppressor of
      Statement
      Reference

      Alkbh81-IC is a non-suppressor of NMJ bouton | increased number | larval stage phenotype of Sps2EY00228

      (Madhwani et al., 2024)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ALKBH81-IC
      (Madhwani et al., 2024)
      ALKBH8<up>1-Interfering Cassette</up>
      (Madhwani et al., 2024)
      Alkbh81-IC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)