FlyBase Allele Report: Dmel\Bcat[Δ]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Bcat^Δ

General Information

Symbol

Dmel\Bcat^Δ

Species

D. melanogaster

Name

FlyBase ID

FBal0407025

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Wu et al., 2025)

Mutagen

(Wu et al., 2025)

Progenitor genotype

Associated Insertion(s)

Cytology

Description

Insertion of a STOP-loxP-Disc\RFP^3xP3.cUa-loxP-STOP cassette into an exon of endogenous Bcat.

(Wu et al., 2025)

Allele components

Component

Use(s)

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

(Wu et al., 2025)

vacuole | adult stage | increased number

(Wu et al., 2025)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Bcat^Δ has increased mortality during development phenotype, enhanceable by Scer\GAL4^elav.PLu/AMPKα^K57A.UAS

(Wu et al., 2025)

Bcat^Δ has some die during larval stage phenotype, enhanceable by Scer\GAL4^elav.PLu/AMPKα^K57A.UAS

(Wu et al., 2025)

Bcat^Δ has some die during P-stage phenotype, enhanceable by Scer\GAL4^elav.PLu/AMPKα^K57A.UAS

(Wu et al., 2025)

Bcat^Δ has decreased rate of larval locomotory behavior phenotype, enhanceable by Scer\GAL4^elav.PLu/AMPKα^K57A.UAS

(Wu et al., 2025)

Suppressed by

Statement

Reference

Bcat^Δ has increased mortality during development phenotype, suppressible | partially by Scer\GAL4^elav.PLu/AMPKα^UAS.mCherry

(Wu et al., 2025)

Bcat^Δ has decreased rate of larval locomotory behavior phenotype, suppressible | partially by Scer\GAL4^elav.PLu/AMPKα^UAS.mCherry

(Wu et al., 2025)

Bcat^Δ has some die during larval stage phenotype, suppressible | partially by Scer\GAL4^elav.PLu/AMPKα^UAS.mCherry

(Wu et al., 2025)

Bcat^Δ has some die during P-stage phenotype, suppressible | partially by Scer\GAL4^elav.PLu/AMPKα^UAS.mCherry

(Wu et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Bcat^Δ

dBCAT^Δ

(Wu et al., 2025)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections