FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\InRRNAi.UAS.cUa
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General Information
Symbol
Dmel\InRRNAi.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0407448
Feature type
allele
Associated gene
Dmel\InR
Associated Insertion(s)
Carried in Construct
P{UAS-InR.RNAi.U}
Also Known As
InR RNAi
Key Links
Transgenic product class
RNAi_reagent
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-InR.RNAi.U}
Cytology
Description

UAS regulatory sequences drive expression of an RNAi construct targeting InR.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
InR
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Machado-Joseph disease
      modeled by Hsap\ATXN3tr.Q78.UAS.Tag:HA
      (Raj and Sarkar, 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Third instar larvae expressing InRdsRNA.UAS.cUa under the control of Scer\GAL4AB1 show significantly smaller salivary gland cells without changes in the number of cells, as compared to controls.

      (Sharma et al., 2019)

      Expression of anoxNIG.1704R under the control of Scer\GAL4anox.PR (in larvae and adults) or Scer\GAL4elav.PU (in larvae) leads to a decrease in feeding activities when compared to controls.

      (Ryuda et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      InRRNAi.UAS.cUa
      InRVDRC.cUa
      InRdsRNA.Scer\UAS.cUa
      InRdsRNA.UAS.cUa
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0302210
      • FBal0340426
      References (9)