A W422term amino acid change has been introduced into endogenous Naglu, equivalent to a W404term change in Hsap\NAGLU (associated with Mucopolysaccharidosis IIIB disorder).
A W422term amino acid change has been introduced into the endogenous CG13397 locus. This change is equivalent to a W404term change in the orthologous human NAGLU gene, a variant that is associated with Mucopolysaccharidosis III B (Sanfilippo syndrome B).
G8410201A
W422term | Naglu-PA; W422term | Naglu-PB
W422term
A W422term amino acid change has been introduced into the endogenous CG13397 locus. This change is equivalent to a W404term change in the orthologous human NAGLU gene, a variant that is associated with Mucopolysaccharidosis III B (Sanfilippo syndrome B). G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.
