FlyBase Allele Report: Dmel\otu[KO-M7]

General Information

Symbol

Dmel\otu^KO-M7

Species

D. melanogaster

Name

FlyBase ID

FBal0408346

Feature type

allele

Associated gene

Dmel\otu

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Mercer et al., 2025)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | oogenesis (with otu^KO-M6)

(Mercer et al., 2025)

Phenotype Manifest In

female germline cell | decreased number (with otu^KO-M6)

(Mercer et al., 2025)

ovariole (with otu^KO-M6)

(Mercer et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

otu^KO-M6/otu^KO-M7 has decreased cell number | oogenesis phenotype, non-enhanceable by bbn^KO

(Mercer et al., 2025)

NOT suppressed by

Statement

Reference

otu^KO-M6/otu^KO-M7 has decreased cell number | oogenesis phenotype, non-suppressible by bbn^KO

(Mercer et al., 2025)

NOT Enhancer of

Statement

Reference

otu^KO-M6/otu^KO-M7 is a non-enhancer of decreased cell number | oogenesis phenotype of bbn^KO

(Mercer et al., 2025)

NOT Suppressor of

Statement

Reference

otu^KO-M6/otu^KO-M7 is a non-suppressor of decreased cell number | oogenesis phenotype of bbn^KO

(Mercer et al., 2025)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

otu^KO-M6/otu^KO-M7 has ovariole phenotype, non-enhanceable by bbn^KO

(Mercer et al., 2025)

otu^KO-M6/otu^KO-M7 has female germline cell | decreased number phenotype, non-enhanceable by bbn^KO

(Mercer et al., 2025)

NOT suppressed by

Statement

Reference

otu^KO-M6/otu^KO-M7 has ovariole phenotype, non-suppressible by bbn^KO

(Mercer et al., 2025)

otu^KO-M6/otu^KO-M7 has female germline cell | decreased number phenotype, non-suppressible by bbn^KO

(Mercer et al., 2025)

NOT Enhancer of

Statement

Reference

otu^KO-M6/otu^KO-M7 is a non-enhancer of ovariole phenotype of bbn^KO

(Mercer et al., 2025)

otu^KO-M6/otu^KO-M7 is a non-enhancer of female germline cell | decreased number phenotype of bbn^KO

(Mercer et al., 2025)

NOT Suppressor of

Statement

Reference

otu^KO-M6/otu^KO-M7 is a non-suppressor of ovariole phenotype of bbn^KO

(Mercer et al., 2025)

otu^KO-M6/otu^KO-M7 is a non-suppressor of female germline cell | decreased number phenotype of bbn^KO

(Mercer et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

M7 otu^KO

(Mercer et al., 2025)

otu^KO-M7

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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