FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Kdm5Q19
Open Close
General Information
Symbol
Dmel\Kdm5Q19
Species
D. melanogaster
Name
FlyBase ID
FBal0408792
Feature type
allele
Associated gene
Dmel\Kdm5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Herz and Bergmann, 2024)
Mutagen
ethyl methanesulfonate
(Herz and Bergmann, 2024)
Progenitor genotype
Cytology
Description

Amino acid replacement: ?1526term.

(Herz and Bergmann, 2024)

Premature STOP codon at codon 1,526 in Kdm5.

(Herz and Bergmann, 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:5,991,582..5,991,582 [-]
Nucleotide change:

G5991582A

Amino acid change:

W1526term | Kdm5-PA; W1526term | Kdm5-PB; W1526term | Kdm5-PC; W1526term | Kdm5-PD; W1526term | Kdm5-PE; W1526term | Kdm5-PF

Reported amino acid change:

?1526term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Herz and Bergmann, 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Kdm5Q19/Kdm5Q19 is a suppressor | partially of eye | somatic clone - tissue specific phenotype of hidGMR.PG

      (Herz and Bergmann, 2024)
      NOT Suppressor of
      Statement
      Reference

      Kdm5Q19/Kdm5Q19 is a non-suppressor of eye | somatic clone - tissue specific phenotype of hidAla5.GMR

      (Herz and Bergmann, 2024)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Kdm5Q19
      (Herz and Bergmann, 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)