FlyBase Allele Report: Dmel\scny[C181S-2]

General Information

Symbol

Dmel\scny^C181S-2

Species

D. melanogaster

Name

FlyBase ID

FBal0410093

Feature type

allele

Associated gene

Dmel\scny

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Coirry et al., 2025)

Progenitor genotype

Cytology

Description

Amino acid replacement: C181S.

(Coirry et al., 2025)

The C181S mutation is introduced into endogenous scny.

(Coirry et al., 2025)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body weight | adult stage (with scny^C181S-1)

(Coirry et al., 2025)

decreased size | adult stage (with scny^C181S-1)

(Coirry et al., 2025)

female semi-fertile (with scny^C181S-1)

(Coirry et al., 2025)

male sterile (with scny^C181S-1)

(Coirry et al., 2025)

viable (with scny^C181S-1)

(Coirry et al., 2025)

Phenotype Manifest In

seminal vesicle (with scny^C181S-1)

(Coirry et al., 2025)

wing (with scny^C181S-1)

(Coirry et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

scny^C181S-2/scny^C181S-1 has decreased size | adult stage phenotype, enhanceable by Myc^JF01761/Scer\GAL4^nub-AC-62

(Coirry et al., 2025)

NOT Enhanced by

Statement

Reference

scny^C181S-2/scny^C181S-1 has decreased body weight | adult stage phenotype, non-enhanceable by Myc^GFP.FPTB

(Coirry et al., 2025)

NOT suppressed by

Statement

Reference

scny^C181S-2/scny^C181S-1 has decreased body weight | adult stage phenotype, non-suppressible by Myc^GFP.FPTB

(Coirry et al., 2025)

scny^C181S-2/scny^C181S-1 has decreased size | adult stage phenotype, non-suppressible by Scer\GAL4^nub-AC-62/ago^HMS00111

(Coirry et al., 2025)

Enhancer of

Statement

Reference

scny^C181S-2/scny^C181S-1 is an enhancer of decreased size | adult stage phenotype of Myc^JF01761, Scer\GAL4^nub-AC-62

(Coirry et al., 2025)

Other

Statement

Reference

Myc^P0, scny^C181S-2/scny^C181S-1 has increased mortality during development phenotype

(Coirry et al., 2025)

Phenotype Manifest In

Enhanced by

Statement

Reference

scny^C181S-2/scny^C181S-1 has wing phenotype, enhanceable by Myc^JF01761/Scer\GAL4^nub-AC-62

(Coirry et al., 2025)

NOT suppressed by

Statement

Reference

scny^C181S-2/scny^C181S-1 has wing phenotype, non-suppressible by Scer\GAL4^nub-AC-62/ago^HMS00111

(Coirry et al., 2025)

Enhancer of

Statement

Reference

scny^C181S-2/scny^C181S-1 is an enhancer of wing phenotype of Myc^JF01761, Scer\GAL4^nub-AC-62

(Coirry et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dUsp36^C181S-2

(Coirry et al., 2025)

scny^C181S-2

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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