FlyBase Allele Report: Dmel\CG5953[UAS.l]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\CG5953^UAS.l

General Information

Symbol

Dmel\CG5953^UAS.l

Species

D. melanogaster

Name

FlyBase ID

FBal0410998

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-CG5953.l}

Key Links

Transgenic product class

(Hu et al., 2025)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Hu et al., 2025)

Mutagen

in vitro construct

(Hu et al., 2025)

Progenitor genotype

Carried in construct

P{UAS-CG5953.l}

Cytology

Description

UASt regulatory sequences drive expression of the long isoform of CG5953.

(Hu et al., 2025)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | adult stage, with Scer\GAL4^esg.PU

(Hu et al., 2025)

decreased cell size | adult stage, with Scer\GAL4^esg.PU

(Hu et al., 2025)

Phenotype Manifest In

adult enteroendocrine cell | decreased number, with Scer\GAL4^esg.PU

(Hu et al., 2025)

adult midgut, with Scer\GAL4^esg.PU

(Hu et al., 2025)

intestinal stem cell | decreased number, with Scer\GAL4^esg.PU

(Hu et al., 2025)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of increased cell number | adult stage phenotype of Scer\GAL4^esg.PU, upd1^UAS.cUa

(Hu et al., 2025)

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of abnormal cell shape | adult stage phenotype of Scer\GAL4^esg.PU, upd1^UAS.cUa

(Hu et al., 2025)

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of increased cell number | adult stage phenotype of Ptp61F^TH03037.N, Scer\GAL4^esg.PU

(Hu et al., 2025)

Phenotype Manifest In

Suppressor of

Statement

Reference

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of intestinal stem cell | increased number phenotype of Scer\GAL4^esg.PU, upd1^UAS.cUa

(Hu et al., 2025)

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of adult midgut phenotype of Scer\GAL4^esg.PU, upd1^UAS.cUa

(Hu et al., 2025)

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of adult enteroendocrine cell | increased number phenotype of Ptp61F^TH03037.N, Scer\GAL4^esg.PU

(Hu et al., 2025)

CG5953^UAS.l, Scer\GAL4^esg.PU is a suppressor of adult midgut phenotype of Ptp61F^TH03037.N, Scer\GAL4^esg.PU

(Hu et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

CG5953^UAS.l

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections