FlyBase Allele Report: Dmel\nrv2[ccp-34]

General Information

Symbol

Dmel\nrv2^ccp-34

Species

D. melanogaster

Name

FlyBase ID

FBal0414207

Feature type

allele

Associated gene

Dmel\nrv2

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Matsumoto et al., 2026)

Progenitor genotype

Cytology

Description

Amino acid replacement: E250K.

(Matsumoto et al., 2026)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | larval stage | somatic clone - tissue specific | conditional

(Matsumoto et al., 2026)

Phenotype Manifest In

eye disc | larval stage | somatic clone - tissue specific | conditional

(Matsumoto et al., 2026)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, non-enhanceable by Scer\GAL4^Act.PU/Xrp1^HMS00053

(Matsumoto et al., 2026)

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, non-enhanceable by Scer\GAL4^Act.PU/Atg1^JF02273

(Matsumoto et al., 2026)

Suppressed by

Statement

Reference

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/rpr^RNAi.RHG.UAS/grim^RNAi.RHG.UAS/hid^RNAi.RHG.UAS

(Matsumoto et al., 2026)

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/bsk^K53R.UAS

(Matsumoto et al., 2026)

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/grnd^extra.UAS

(Matsumoto et al., 2026)

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by egr^RNAi.UAS/Scer\GAL4^r4

(Matsumoto et al., 2026)

NOT suppressed by

Statement

Reference

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, non-suppressible by Scer\GAL4^Act.PU/Xrp1^HMS00053

(Matsumoto et al., 2026)

nrv2^ccp-34 has cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype, non-suppressible by Scer\GAL4^Act.PU/Atg1^JF02273

(Matsumoto et al., 2026)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, non-enhanceable by Scer\GAL4^Act.PU/Xrp1^HMS00053

(Matsumoto et al., 2026)

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, non-enhanceable by Scer\GAL4^Act.PU/Atg1^JF02273

(Matsumoto et al., 2026)

Suppressed by

Statement

Reference

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/grnd^extra.UAS

(Matsumoto et al., 2026)

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/bsk^K53R.UAS

(Matsumoto et al., 2026)

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by egr^RNAi.UAS/Scer\GAL4^r4

(Matsumoto et al., 2026)

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, suppressible by Scer\GAL4^Act.PU/rpr^RNAi.RHG.UAS/grim^RNAi.RHG.UAS/hid^RNAi.RHG.UAS

(Matsumoto et al., 2026)

NOT suppressed by

Statement

Reference

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, non-suppressible by Scer\GAL4^Act.PU/Atg1^JF02273

(Matsumoto et al., 2026)

nrv2^ccp-34 has eye disc | larval stage | somatic clone - tissue specific | conditional phenotype, non-suppressible by Scer\GAL4^Act.PU/Xrp1^HMS00053

(Matsumoto et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

nrv2^ccp-34 is rescued by Scer\GAL4^Act.PU/nrv2^{1.UAS.Tag:FLAG}

(Matsumoto et al., 2026)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ccp-34

(Matsumoto et al., 2026)

nrv2^ccp-34

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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