An elav promoter regulates expression of a GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain). An internal ribosomal entry site (IRES) from the Ubx gene followed by DsRed(Unk) coding sequence is present downstream of the hemidriver sequence, but this is not expressed in the nervous system.
An elav promoter regulates expression of a GAL4(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the GAL4 activation domain). The hemidriver sequence includes the Tag:NLS(SV40-largeT) nuclear localization signal. An internal ribosomal entry site (IRES) from the Ubx gene followed by DsRed(Unk) coding sequence is present downstream of the hemidriver sequence, but this is not expressed in the nervous system.
ScerGAL4DBD.elav drives expression pan-neuronally, recapitulating the elav expression pattern, when combined with ScerGAL4AD.elav or HsimVP16AD.elav in a split-GAL4 system.
ScerGAL4AD.elav drives expression pan-neuronally, recapitulating the elav expression pattern, when combined with ScerGAL4DBD.elav in a split-GAL4 system.