FB2026_02 , released June 18, 2026
Gene Group: INHIBITOR OF APOPTOSIS
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General Information
Name
INHIBITOR OF APOPTOSIS
Species
D. melanogaster
Symbol
IAP
FlyBase ID
FBgg0000064
Date last reviewed
2014-07-27
Number of members
4
Description
Description
Inhibitor of APoptosis (IAP) proteins are defined by the presence of one or more BIR (baculoviral IAP repeat) domains. Not all IAPs inhibit apoptosis, but some interact with and inhibit caspases via their BIR domains. This interaction is displaced by RHG protein binding. (Adapted from FBrf0215539).
Notes on Group
Source Material
The INHIBITOR OF APOPTOSIS Gene Group has been compiled using the following publication(s): Xu et al., 2009 .
Key Gene Ontology (GO) terms
Molecular Function
caspase binding
Biological Process
negative regulation of apoptotic process
Cellular Component
Related Gene Groups
Other related group(s)
CASPASES
INHIBITOR OF APOPTOSIS UBIQUITIN LIGASES
RHG PROTEINS
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
IAP
INHIBITOR OF APOPTOSIS
BIR family
Baculovirus inhibitory repeat family
Baculoviral IAP repeat containing proteins
Inhibitor of apoptosis proteins
BIR
Secondary FlyBase ID(s)
References (2)