FB2026_02 , released June 18, 2026
Gene Group: WNTs
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General Information
Name
WNTs
Species
D. melanogaster
Symbol
WNT
FlyBase ID
FBgg0000162
Date last reviewed
2026-02-03
Number of members
7
Description
Description
WNTs are evolutionarily conserved secreted Cys-rich glycoproteins, defined by sequence homology to the original members of the family - Wnt1 in mouse and wingless (wg) in Drosophila. They are extracellular ligands for members of the Frizzled family of receptors as well as other receptors. (Adapted from PMID:23151663).
Notes on Group
Source Material
The WNTs Gene Group has been compiled using the following publication(s): Mele and Johnson, 2019, Reynaud et al., 2015, Herr and Basler, 2012, and Llimargas and Lawrence, 2001 .
Key Gene Ontology (GO) terms
Molecular Function
frizzled binding
receptor ligand activity
Biological Process
Wnt signaling pathway
Cellular Component
extracellular region
Related Gene Groups
Parent group(s)
RECEPTOR LIGANDS
Other related group(s)
FRIZZLED-TYPE RECEPTORS
WNT-TCF SIGNALING PATHWAY CORE COMPONENTS
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
WNT
WNTs
Wingless-type MMTV integration site
Wingless-type mouse mammary tumour virus integration site
DWnt
Secondary FlyBase ID(s)
References (5)