Gene Group: DEUBIQUITINASES

General Information

Name

DEUBIQUITINASES

Species

D. melanogaster

Symbol

DUB

FlyBase ID

FBgg0000165

Date last reviewed

2014-02-24

Number of members

Description

Deubiquitinases (DUBs) catalyze the proteolytic removal of ubiquitin from ubiquitin chains and ubiquitinated proteins. Most are cysteine peptidases, though the JAMM domain-containing deubiquitinases are metallopeptidases. (Adapted from PMID:19626045 and PMID:19489724.)

Notes on Group

Source Material

The DEUBIQUITINASES Gene Group has been compiled using the following publication(s): Erven et al., 2022, Páhi et al., 2022, Badmos et al., 2021, Louis et al., 2015, Engel et al., 2014, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, and Rawlings and Barrett, 1996- .

Key Gene Ontology (GO) terms

Molecular Function

deubiquitinase activity

Biological Process

protein deubiquitination

Cellular Component

Related Gene Groups

Parent group(s)

UBIQUITIN-LIKE PROTEIN PEPTIDASES

Component group(s)

CYSTEINE-TYPE DEUBIQUITINASES

JAMM DEUBIQUITINASES