FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: POLYCOMB GROUP COMPLEXES
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General Information
Name
POLYCOMB GROUP COMPLEXES
Species
D. melanogaster
Symbol
PCG-C
FlyBase ID
FBgg0000309
Date last reviewed
2017-10-10
Number of members
19
Description
Description
The Polycomb group (PcG) proteins are epigenetic regulators, best characterized for the repression of Hox gene expression. PcG proteins form complexes that regulate chromatin structure. (Adapted from FBrf0220020 and FBrf0228921).
Notes on Group
Source Material
The POLYCOMB GROUP COMPLEXES Gene Group has been compiled using the following publication(s): Fischer et al., 2022, Kassis et al., 2017, Piunti and Shilatifard, 2016, Grossniklaus and Paro, 2014, Lanzuolo and Orlando, 2012, Margueron and Reinberg, 2011, Scheuermann et al., 2010, Lo et al., 2009, Lagarou et al., 2008, and Klymenko et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
heterochromatin formation
Cellular Component
PcG protein complex
Related Gene Groups
Component group(s)
dRING-ASSOCIATED FACTORS COMPLEX
PHO REPRESSIVE COMPLEX - PHOL VARIANT
PHO REPRESSIVE COMPLEX - PHO VARIANT
POLYCOMB REPRESSIVE COMPLEX 1, PSC VARIANT
POLYCOMB REPRESSIVE COMPLEX 1, SU(Z)2 VARIANT
POLYCOMB REPRESSIVE COMPLEX 2, JARID2-JING VARIANT
POLYCOMB REPRESSIVE COMPLEX 2, PCL VARIANT
POLYCOMB REPRESSIVE DEUBIQUITINASE COMPLEX
Other related group(s)
HOX GENE COMPLEX
POLYCOMB GROUP RECRUITERS/DNA-BINDING PROTEINS
TRITHORAX GROUP COMPLEXES
Members (19)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[The Polycomb and Trithorax page, Cavalli lab](http://www.igh.cnrs.fr/equip/cavalli/link.PolycombTeaching.html)

Synonyms and Secondary IDs
Synonym(s)
PCG-C
POLYCOMB GROUP COMPLEXES
Polycomb complexes
PcG
PRC
Secondary FlyBase ID(s)
References (11)