FlyBase Gene Report: Dmel\eor

General Information

Symbol

Dmel\eor

Species

D. melanogaster

Name

extra organs

Annotation Symbol

Feature Type

gene

FlyBase ID

FBgn0000580

Gene Model Status

Unannotated

Stock Availability

6 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Red Book
Interactive Fly

Also Known As

A7, lA7, eo, E54

Function

Gene Ontology (GO) Annotations (2 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in gastrulation involving germ band extension

inferred from mutant phenotype

(Perrimon et al., 1989)

involved_in imaginal disc development

inferred from mutant phenotype

(Perrimon et al., 1989)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

eo: extra organs

Homozygous lethal; in rare surviving genotypes, a leg may be branched or completely duplicated, an antenna or arista duplicated, or triplicated; eyes and wings malformed; usually only eye effect present. Phenotype expressed in presence of y+Ymal126. Homozygous germ-line clones are maternal-effect lethals; eo25 clones produce embryos with head defects and ventral holes; rescuable by eo+ sperm. eo1 and eo28 clones produce embryos that are U-shaped as a result of incomplete germ-band retraction; have poor cuticle differentiation and ventral holes. eo27 clones also form ovarian tumors after approximately six days.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eor using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\eor in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\eor

View exonic expression by tissue for Dmel\eor

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 40 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of eor

Transgenic constructs containing regulatory region of eor

Aberrations (Deficiencies and Duplications) ( 272 )

Inferred from experimentation ( 272 )

Gene disrupted in

Df(1)14-11

(Munoz, 2003.12.10)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2003.12.10, Kramers et al., 1991, Perrimon et al., 1989, Rahman and Lindsley, 1981, Schalet and Lefevre, 1973)

Df(1)17-228

(Munoz, 2004.1.5)

Df(1)17-241

(Munoz, 2003.12.10)

Df(1)17-244

(Munoz, 2004.1.5)

Df(1)17-257

(Maleszka et al., 1996, Russell et al., 1992, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Schalet and Lefevre, 1973)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)18-36

(Munoz, 2004.1.5)

Df(1)19-2

(Munoz, 2004.1.5)

Df(1)19-18

(Munoz, 2004.1.5, Munoz, 2003.12.10)

Df(1)26B

(Perrimon et al., 1989)

Df(1)156

(Paradi et al., 1983)

Df(1)216

(Paradi et al., 1983)

Df(1)217

(Paradi et al., 1983)

Df(1)A53

(Perrimon et al., 1989)

Df(1)B12

(Munoz, 2003.12.10, Robert et al., 2001, Prud'homme et al., 1995, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B82

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B155

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)C74

(Miklos and de Couet, 1990, Perrimon et al., 1989)

Df(1)D5

(Eeken et al., 1985)

Df(1)D43L1

(Kramers et al., 1991, Perrimon et al., 1989, Eeken et al., 1985, Kramers et al., 1983, Paradi et al., 1983, Rahman and Lindsley, 1981, Schalet and Finnerty, 1968)

Df(1)DCB1-35b

(Prud'homme et al., 1995, Perrimon et al., 1989, Zusman et al., 1985)

Df(1)DCB1-35c

(Schalet and Finnerty, 1968)

Df(1)GA33

(Perrimon et al., 1989)

Df(1)GA40

(Perrimon et al., 1989)

Df(1)GE263

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HM45

(Kramers et al., 1983)

Df(1)HM49

(Kramers et al., 1983)

Df(1)HM50

(Kramers et al., 1983)

Df(1)JC4

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)JC12

(Perrimon et al., 1989)

Df(1)JC77

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)l11

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)LB6

(Robert et al., 2001, Prud'homme et al., 1995, Perrimon et al., 1989, Schalet and Lefevre, 1973)

Df(1)LB7

(Perrimon et al., 1989)

Df(1)LB23

(Perrimon et al., 1989)

Df(1)mal3

(Kramers et al., 1991, Kramers et al., 1983, Rahman and Lindsley, 1981, Chovnick et al., 1969)

Df(1)mal4

(Chovnick et al., 1969, Schalet and Finnerty, 1968)

Df(1)mal6

(Kramers et al., 1991, Kramers et al., 1983, Paradi et al., 1983, Schalet and Lefevre, 1973, Chovnick et al., 1969, Schalet and Finnerty, 1968, Schalet and Finnerty, 1968)

Df(1)mal7

(Chovnick et al., 1969)

Df(1)mal9

(Chovnick et al., 1969)

Df(1)mal12

(Zusman et al., 1985, Paradi et al., 1983, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980, Chovnick et al., 1969)

Df(1)mal13

(Chovnick et al., 1969, Schalet and Finnerty, 1968)

Df(1)n17-8

(Munoz, 2004.1.5)

Df(1)N77

(Perrimon et al., 1989)

Df(1)Q219

(Lifschytz and Falk, 1969)

Df(1)Q408

(Lifschytz and Falk, 1969)

Df(1)R1

(Rahman and Lindsley, 1981)

Df(1)R4

(Rahman and Lindsley, 1981)

Df(1)R5

(Rahman and Lindsley, 1981)

Df(1)R-9-1

(Lifschytz and Falk, 1969)

Df(1)R9

(Rahman and Lindsley, 1981)

Df(1)R-10-5

(Lifschytz and Falk, 1969)

Df(1)R11

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R19

(Rahman and Lindsley, 1981)

Df(1)R22

(Prud'homme et al., 1995)

Df(1)R25

(Rahman and Lindsley, 1980)

Df(1)R29

(Rahman and Lindsley, 1981)

Df(1)R34

(Rahman and Lindsley, 1981)

Df(1)R37

(Rahman and Lindsley, 1981)

Df(1)R39

(Rahman and Lindsley, 1981)

Df(1)R44

(Rahman and Lindsley, 1980)

Df(1)R45

(Rahman and Lindsley, 1981)

Df(1)R48

(Rahman and Lindsley, 1981)

Df(1)S54

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)su(f)754

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)7085

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)9122

(Lifschytz and Yakobovitz, 1978)

Df(1)T100

(Paradi et al., 1983)

Df(1)T101

(Paradi et al., 1983)

Df(1)T103

(Paradi et al., 1983)

Df(1)T107

(Paradi et al., 1983)

Df(1)T113

(Paradi et al., 1983)

Df(1)T122

(Paradi et al., 1983)

Df(1)T123

(Paradi et al., 1983)

Df(1)T124

(Paradi et al., 1983)

Df(1)T130

(Paradi et al., 1983)

Df(1)T138

(Paradi et al., 1983)

Df(1)wl-2

(Lifschytz and Falk, 1969)

Df(1)yl-1

(Lifschytz and Falk, 1969)

Dp(1;Y)y⁺mal¹⁰⁷

(Chovnick et al., 1969)

Dp(1;Y)y⁺mal¹¹⁸

(Chovnick et al., 1969)

Dp(1;Y)y⁺mal¹²⁶

(Lifschytz and Yakobovitz, 1978, Schalet, 1972, Chovnick et al., 1969)

Gene not disrupted in

Df(1)2/19B

(Maleszka et al., 1996, Miklos and de Couet, 1990, Perrimon et al., 1989)

Df(1)13C3

(Schalet and Lefevre, 1973)

Df(1)15-13

(Munoz, 2003.12.10)

Df(1)16-1-80

(Munoz, 2003.12.10)

Df(1)16-2-13

(Robert et al., 2001, Prud'homme et al., 1995, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)16-2-14

(Munoz, 2003.12.10)

Df(1)16-3-20

(Munoz, 2003.12.10)

Df(1)16-3-22

(Miklos et al., 1987)

Df(1)16-3-34

(Munoz, 2003.12.10)

Df(1)16-3-35

(Munoz, 2003.12.10, Kramers et al., 1991, Perrimon et al., 1989, Miklos et al., 1987, Eeken et al., 1985, Paradi et al., 1983)

Df(1)16-3-53

(Munoz, 2004.1.5)

Df(1)16-3-93

(Munoz, 2003.12.10)

Df(1)16-3-211

(Munoz, 2003.12.10)

Df(1)16-129

(Maleszka et al., 1996, Prud'homme et al., 1995, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Eeken et al., 1985, Miklos et al., 1984)

Df(1)16-185

(Rahman and Lindsley, 1981)

Df(1)17-25

(Munoz, 2003.12.10)

Df(1)17-87

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)17-148

(Prud'homme et al., 1995, Perrimon et al., 1989, Rahman and Lindsley, 1981)

Df(1)17-351

(Munoz, 2003.12.10, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)17-408

(Rahman and Lindsley, 1981)

Df(1)17-439

(Munoz, 1992, Schalet and Lefevre, 1973)

Df(1)17-456

(Munoz, 2004.1.5)

Df(1)17-466

(Schalet and Lefevre, 1973)

Df(1)18-6

(Munoz, 2003.12.10)

Df(1)18-76

(Munoz, 2004.1.5)

Df(1)18-80

(Munoz, 2004.1.5)

Df(1)48-2

(Zusman et al., 1985)

Df(1)120

(Paradi et al., 1983)

Df(1)127

(Paradi et al., 1983)

Df(1)136

(Paradi et al., 1983)

Df(1)167

(Paradi et al., 1983)

Df(1)208

(Paradi et al., 1983)

Df(1)218

(Paradi et al., 1983)

Df(1)228

(Paradi et al., 1983)

Df(1)278.4B1

(Perrimon et al., 1985)

Df(1)A19

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A33

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A58

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A118

(Kramers et al., 1991, Perrimon et al., 1989, Miklos et al., 1987, Eeken et al., 1985, Miklos et al., 1984, Kramers et al., 1983, Paradi et al., 1983, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A122

(Schalet and Lefevre, 1973, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A129

(Lifschytz and Falk, 1968)

Df(1)A161

(Lifschytz and Falk, 1968)

Df(1)A200

(Lifschytz and Falk, 1968)

Df(1)A209

(Zusman et al., 1985, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)A211

(Lifschytz and Falk, 1968)

Df(1)B18

(Lifschytz and Falk, 1968)

Df(1)B47

(Lifschytz and Falk, 1968)

Df(1)B56

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B57

(Munoz, 2003.12.10, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Miklos et al., 1984, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B85

(Lifschytz and Falk, 1968)

Df(1)B99

(Lifschytz and Falk, 1968)

Df(1)B111

(Munoz, 2003.12.10, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B179

(Lifschytz and Falk, 1968)

Df(1)B182

(Lifschytz and Falk, 1968)

Df(1)B199

(Lifschytz and Falk, 1968)

Df(1)B214

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)B225

(Lifschytz and Falk, 1968)

Df(1)B240

(Lifschytz and Falk, 1968)

Df(1)B255

(Lifschytz and Falk, 1968)

Df(1)B264

(Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)DCB1-35c

(Robert et al., 2001, Prud'homme et al., 1995, Perrimon et al., 1989, Miklos et al., 1987, Schalet and Lefevre, 1973)

Df(1)EA113

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)flam-l9

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)GA22

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)GA37

(Perrimon et al., 1989)

Df(1)GA42

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)GA90

(Zusman et al., 1985, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)GA104

(Maleszka et al., 1996, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)GA131

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HC279

(Perrimon et al., 1989)

Df(1)HF359

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HM5

(Kramers et al., 1983)

Df(1)HM8

(Kramers et al., 1983)

Df(1)HM44

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Miklos et al., 1986, Kramers et al., 1983)

Df(1)HM47

(Kramers et al., 1983)

Df(1)HM418

(Kramers et al., 1983)

Df(1)HM422

(Kramers et al., 1983)

Df(1)HM430

(Perrimon et al., 1989)

Df(1)HM444

(Kramers et al., 1983)

Df(1)HM455

(Kramers et al., 1983)

Df(1)JA21

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)JA117

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)K5

(Rahman and Lindsley, 1981)

Df(1)l2

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l3

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l4

(Prud'homme et al., 1995)

Df(1)l5

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l6

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l7

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l8

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l10

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l12

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l13

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l14

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l15

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)l16

(Robert et al., 2001, Prud'homme et al., 1995)

Df(1)M31

(Lifschytz and Yakobovitz, 1978)

Df(1)M158

(Lifschytz and Yakobovitz, 1978)

Df(1)M171

(Lifschytz and Yakobovitz, 1978)

Df(1)M176

(Lifschytz and Yakobovitz, 1978)

Df(1)mal5

(Chovnick et al., 1969)

Df(1)mal7

(Schalet and Finnerty, 1968)

Df(1)mal8

(Kramers et al., 1991, Zusman et al., 1985, Paradi et al., 1983, Chovnick et al., 1969, Schalet and Finnerty, 1968)

Df(1)mal10

(Perrimon et al., 1989, Paradi et al., 1983, Chovnick et al., 1969, Schalet and Finnerty, 1968)

Df(1)mal11

(Chovnick et al., 1969)

Df(1)mal17

(Perrimon et al., 1989, Chovnick et al., 1969)

Df(1)Q38

(Lifschytz and Falk, 1969)

Df(1)Q539

(Prud'homme et al., 1995, Kramers et al., 1991, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Zusman et al., 1985, Miklos et al., 1984, Kramers et al., 1983, Paradi et al., 1983, Schalet and Lefevre, 1973, Lifschytz and Falk, 1969)

Df(1)R2

(Rahman and Lindsley, 1981)

Df(1)R3

(Rahman and Lindsley, 1981)

Df(1)R6

(Rahman and Lindsley, 1981)

Df(1)R7

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R8A

(Rahman and Lindsley, 1981)

Df(1)R8

(Rahman and Lindsley, 1981)

Df(1)R10

(Rahman and Lindsley, 1981)

Df(1)R12

(Rahman and Lindsley, 1981)

Df(1)R13

(Rahman and Lindsley, 1981)

Df(1)R14

(Rahman and Lindsley, 1981)

Df(1)R15

(Rahman and Lindsley, 1981)

Df(1)R16

(Rahman and Lindsley, 1981)

Df(1)R17

(Rahman and Lindsley, 1981)

Df(1)R18

(Rahman and Lindsley, 1981)

Df(1)R20

(Robert et al., 2001, Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R21

(Robert et al., 2001, Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R22

(Rahman and Lindsley, 1981)

Df(1)R23

(Rahman and Lindsley, 1981)

Df(1)R24

(Rahman and Lindsley, 1981)

Df(1)R25

(Rahman and Lindsley, 1981)

Df(1)R26

(Rahman and Lindsley, 1981)

Df(1)R27

(Rahman and Lindsley, 1981)

Df(1)R28

(Rahman and Lindsley, 1981)

Df(1)R30

(Rahman and Lindsley, 1981)

Df(1)R31

(Rahman and Lindsley, 1981)

Df(1)R32

(Rahman and Lindsley, 1981)

Df(1)R33

(Rahman and Lindsley, 1981)

Df(1)R35

(Rahman and Lindsley, 1981)

Df(1)R36

(Rahman and Lindsley, 1981)

Df(1)R38

(Rahman and Lindsley, 1981)

Df(1)R40

(Rahman and Lindsley, 1981)

Df(1)R41

(Rahman and Lindsley, 1981)

Df(1)R42

(Rahman and Lindsley, 1981)

Df(1)R43

(Rahman and Lindsley, 1981)

Df(1)R44

(Robert et al., 2001, Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R46

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R47

(Rahman and Lindsley, 1981)

Df(1)run1112

(Perrimon et al., 1989, Zusman et al., 1985)

Df(1)Sp20A-F

(Schalet, 1986)

Df(1)su(f)4B

(Kramers et al., 1991, Kramers et al., 1983)

Df(1)su(f)724

(Prud'homme et al., 1995, Lifschytz and Yakobovitz, 1978)

Df(1)su(f)733

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)795

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)7009

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)⁵

(Schalet and Lefevre, 1973)

Df(1)T2-14A

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)T105

(Paradi et al., 1983)

Df(1)T106

(Paradi et al., 1983)

Df(1)T110

(Paradi et al., 1983)

Df(1)T114

(Paradi et al., 1983)

Df(1)T136

(Paradi et al., 1983)

Df(1)T137

(Paradi et al., 1983)

Df(1)X-1

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)

Df(1)y-X5

(Rahman and Lindsley, 1981)

Df(1)y-X15

(Kramers et al., 1991, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Dp(1;Y)y⁺mal¹⁰⁸

(Chovnick et al., 1969)

Dp(1;Y)y⁺mal¹¹³

(Chovnick et al., 1969)

Dp(1;Y)y⁺mal¹²⁶

Gene duplicated in

Dp(1;f)3

(Schalet and Finnerty, 1968)

Dp(1;f)52

(Schalet and Finnerty, 1968)

Dp(1;f)mini2

(Prud'homme et al., 1995, Perrimon et al., 1989)

Dp(1;f)mini6

(Prud'homme et al., 1995)

Dp(1;f)mini7

(Prud'homme et al., 1995)

Dp(1;f)mini77

(Miklos and de Couet, 1990, Perrimon et al., 1989)

Dp(1;f)mini-ring

(Perrimon et al., 1989)

Dp(1;Y)59k9-4

(Eeken et al., 1985)

Dp(1;Y)B101

(Perrimon et al., 1989)

Dp(1;Y)mal⁺

(Rahman and Lindsley, 1981, Lifschytz and Falk, 1968)

Dp(1;Y)y⁺mal¹⁰²

(Prud'homme et al., 1995, Perrimon et al., 1989, Chovnick et al., 1969)

Dp(1;Y)y⁺mal¹⁰⁶

(Prud'homme et al., 1995, Miklos and de Couet, 1990)

Dp(1;Y)y⁺mal¹²⁶

(Prud'homme et al., 1995, Kramers et al., 1991, Miklos and de Couet, 1990, Perrimon et al., 1989, Kramers et al., 1983, Rahman and Lindsley, 1981, Schalet and Lefevre, 1973)

Dp(1;Y)y⁺mal¹⁷¹

(Perrimon et al., 1989)

Dp(1;Y)y⁺mal⁺

(Prud'homme et al., 1995, Eeken et al., 1985, Lefevre, 1981)

Ts(1Rt;YLt)B154

(Perrimon et al., 1989)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | germline clone | maternal effect

eor²⁷

lethal | germline clone | maternal effect | recessive

lethal | germline clone | rescuable maternal effect

eor²⁵

lethal | larval stage | recessive

eor¹

lethal | maternal effect

eor²⁷

lethal | recessive

lethal - all die before end of larval stage | maternal effect

eor²⁷

Other Phenotypes

Allele

some die during larval stage | maternal effect

eor²⁷

visible

Phenotype manifest in

Allele

antenna

arista

embryo | germline clone

eor¹

embryonic/first instar larval cuticle | germline clone

eor¹

eye

leg

wing

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (0)

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (0)

Mus musculus (laboratory mouse) (0)

Xenopus tropicalis (Western clawed frog) (0)

Danio rerio (Zebrafish) (0)

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (0)

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:eor. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-[66]

Cytogenetic map

20A1-20A2

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

20A1-20A2

Left limit from inclusion within Df(1)su(f)9122 (FBrf0032163) Right limit from inclusion within Df(1)S54 (FBrf0046783)

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

(Kramers et al., 1983, Schalet, 1972)

1-[66]

Left of (cM)

(Schalet, 1972)

Right of (cM)

Ddx56
mal

(Schalet, 1972)

Notes

Stocks and Reagents

Stocks (6)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

4733

eor²⁵/FM7a

7434

eor^16-2-27/Binsn

8135

y¹ w¹ f¹ eor^16-3-119/Basc

4749

eor²⁸/Dp(1;Y)y⁺mal¹⁰⁶/FM6, Bar⁺

Kyoto

101026

C(1)DX, y¹ w¹ f¹ / eor^S3M / Dp(1;Y)y⁺mal¹⁰⁶

101089

eor¹ / FM6, y² sc⁸ Myc^dm-1 Bar¹ / Dp(1;Y)y⁺mal¹²⁶

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Homozygous lethal; in rare surviving genotypes, a leg may be branched or completely duplicated, an antenna or arista duplicated, or triplicated; eyes and wings malformed; usually only eye effect present. Phenotype expressed in presence of Dp(1;Y)y⁺mal¹²⁶. Homozygous germ-line clones are maternal-effect lethals; eo²⁵ clones produce embryos with head defects and ventral holes; rescuable by eo⁺ sperm. eo¹ and eo²⁸ clones produce embryos that are U-shaped as a result of incomplete germ-band retraction; have poor cuticle differentiation and ventral holes. eo²⁷ clones also form ovarian tumors after approximately six days.

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: eor eo

(FlyBase, 2009-)

Nomenclature comments

The gene symbol "eo" has been changed to "eor" in order to reduce confusion with the "Eo" ("Ecdysone oxidase") gene symbol, from which it differed only by case.

(FlyBase, 2009-)

Etymology

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

(Lifschytz and Falk, 1968)

(Lifschytz and Falk, 1969)

(Kramers et al., 1991, Lefevre and Watkins, 1986, Schalet, 1986, Eeken et al., 1985, Kramers et al., 1983, Lefevre, 1981, Rahman and Lindsley, 1981)

E54

(Bergman et al., 2006, Lifschytz, 1978)

N-30

(Schalet and Finnerty, 1968)

(Morriss et al., 2013)

eor

l(1)17-252

l(1)20Aa

l(1)20Af

l(1)E-54

(Rahman and Lindsley, 1980)

lA7

(Schalet and Singer, 1971, Schalet et al., 1970, Chovnick et al., 1969, Schalet, 1969, Schalet and Finnerty, 1968)

lN-30

(Schalet, 1969)

Name Synonyms

extra organs

(Morriss et al., 2013)

lethal(1)20Af

section 12

(Lifschytz and Falk, 1968)

section 17

(Lifschytz and Falk, 1969)

Secondary FlyBase IDs

FBgn0017382

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (44)

NA

Report Sections