Subject: Drosophila data
Dear colleges,
The Drosophila lab. at the Argentine Atomic
Energy Commission is being closed by the end of
this year. Owing to this I'm in touch with Dr. Kevin
Cook to whom I'm sending some neutron induced
lethals and deletions from the base of the X chromosome
covered by Dp (1;Y) mal+. He will surely get in touch
with you in order to incorporate this information to
the Flybase. The lethals can be divided in four
groups: A, B, C and D.
GROUP A: lethals i) described in the Flybase or
mentioned as alleles or synonyms; ii) no stocks
were available in Bloomington.
GROUP B: lethals that as far as I know do not appear
in the Flybase. Since I think information on their
localization may be of use to those interested in the
proximal end of the X, the mapping details are
provided in the attached file.
GROUP C: lethals, i) mentioned in the Flybase;
ii) with stocks available in Bloomington.
GROUP D: Although fully analyzed, I haven't
published the location of these lethals and deficiencies
(about 20) and I believe they do not appear in the
Flybase. Unfortunately we lost the stocks, and after
giving copies away we also lost their track. Actually,
I don't know if somebody described them or
still have a copy of the stocks. With this in mind I
thought it may be of interest to incorporate the
information on their mapping in the Flybase.
Therefore, if you believe my data on the localization
of the lethals could be useful, please let me know
and I'll be glad to send it.
Please find attached: 1) A letter sent to Dr. Cook;
2) Mapping of GROUP B lethals.
Best regards,
Dr. Enzo R. Munoz
Radiobiologia
Comision Nacional de
Energia Atomica
Av. Gral. Paz 1499
1650 \- San MNartin (Buenos Aires)
Argentina
\--------------------------
GROUP B
Stocks of lethals covered by Dp(1;Y)mal+ that do not appear in the Flybase.
bbl: bb lethal of unknown origin. \-(Fb): The chromosome appears in the Flybase
Lethals and deficiencies whose designation does not start with prefixes 14 to
19 are from Lifschytz and Falk collection. Their location and subsequent
corrections can be found in the following references (by no means exhaustive):
Lifschytz, E. and Falk, R.: Mutation Res. 6, 235-244 (l968); Mutation Res. 8,
(1969) 147-155; DIS 45 (1970), 44. Falk, R., Mutation Res. 20, (1973)
287-290. Lifschytz, E. Mutation Res. 13 (1971) 35-47. Schalet, A. and
Lefevre, G., Chromosoma 44 (1973) 183-202; The Genetics and Biology of
Drosophila, Vol 1b (1976) 847-902
10.-Df(1)16-1-80
Not covered by Dp(1;Y)BSYy+. Lethal with Dfs.B-111 and 17-196 and with
lethals A-200, Q-56, Q-456. Viable with Dfs. B-12, B-57, 16-3-35 (Fb), 17-25
(Fb) and n23 (Fb) and with lethals E-54, 14-1, x-3, 114, P-19,Q-463, X-4,
R-9-18, 3-Des. Normal with bbl.
bk1: Between eo and wap. Left limit from non-inclusion of l(1)E-54 (eo);
right, from inclusion of A-200 (wap).
bk2: Between uncl and l(1)114 (fog). Left limit from inclusion of uncl; right,
from non-inclusion of l(1)114.
Deficiency with similar break points limits: 16-2-13 (Fb)
11.-Df(1)16-3-20
Not covered by Dp(1;Y)BSYy+. Lethal with Df(1)B-111 and with lethals
A-200, Q-56, 114, X-3, P-19, Q-463, X-4, R-9-18, 3-Des, and bbl. Semi-lethal
with Q-456 (uncl). Viable with Dfs. B-57, B-12, 16-3-35 (Fb), 17-25 (Fb) and
17-322 and l(1)E-54.
bk1: Between eo and wap. Left limit from non-inclusion of l(1)E-54 (eo); right
from inclusion of A-200 (wap).
bk2: To the right of bb ?, is lethal with bbl.
Deficiencies with similar break points limits: 16-2-14, 15-13, 15-17, 18-67
12.-Df(1)15-13
See above Df(1)16-3-20
13.-Df(1)16-3-34
Not covered by Dp(1;Y)BSYy+. Letal with Df(1)B-111 and with lethals A-200
and Q-56. Viable with Dfs. B-57, B-12, 16-3-35 (Fb), 17-25 (Fb), 17-196 and
with lethals E-54, Q-456, 114, x-3, P-19, Q-463, x-4, R-9-18, 3-Des, 14-1.-
Normal with bbl.
bk 1: Between eo and wap. Left limit from non-inclusion of l(1)E54, l(1)14-1
(eo); right from inclusion of l(1)A-200 (wap).
bk 2: Between l(1)Q-56 and uncl. Left limit from inclusion of l(1)Q56; right
from non-inclusion of Df(1)17-196 and l(1)Q-456 (uncl).
Deficiency with similar break points limits: Df(1)17-326
14.-Df(1)16-3-93
Not covered by Dp(1;Y)BSYy+. Lethal with Df(1)B-111 and with lethals
A-200, Q-56, 114, x-3, P-19, Q-463, x-4, R-9-18, 3-Des. Semi-lethal with
l(1)Q-456 (uncl). Viable with Dfs.B-57, B-12, 16-3-35 (Fb), 17-25 (Fb), 17-322
and l(1)E-54. Normal with bbl.
bk 1: Between eo and wap. Left limit from non-inclusion of l(1)E-54 (eo) and
Df(l)B-12; right from inclusion of A-200 (wap).
bk 2: Between su(f) and bb. Left limit from inclusion of 3-Des (su(f)); right
from non-inclusion of bb.
Dfs. with similar break points: 16-2-17, 16-3-71, 16-3-145, 18-6, 17-319,
18-57, 18-30 (male sterile), 17-459 (male sterile).
l5.-Df(1)18-6
See above Df(1)16-3-93
16.-Df(1)16-3-211
Not covered by Dp(1;Y)BSYy+. Lethal with Df(1)B-111 and with lethals
A-200, Q-56, 114, x-3, P-19, Q-463, x-4, R-9-18, and 3-Des. Semi-lethal with
l(1)Q-456 (uncl). Viable with Dfs. B-57, B-12, 16-3-35 (Fb), 17-25 (Fb),
17-322 and with l(1)E-54 (eo). It shows bb with bbl
.
bk1: Between eo and wap. Left limit from non-inclusion of l(1)E54 (eo) and
Df(1)B-12; right from inclusion of l(1)A-200.
bk2: Disrupt bb.
17.-Df(1)14-11
Not covered by Dp(1;Y)BSYy+. Lethal with Dfs. B-111, B-57, B-12, 16-3-35
(Fb), T2-14-A, and with lethals A-200, Q-56, Q-456, B-56, B-214, W-2, W-4,
LB20, E-81, AA-33, 17-62 (Fb), 14-1, 16-3-212 (Fb). Viable with Dfs. 17-25
(Fb), 18-61, mal-10 and with lethals 114, x-3, P-19, Q-463, x-4, R-9-18,
3-Des. Normal with ot and bbl.
bk1: Between mell and l(1)AA-33 (leg, run). Left limit from non-inclusion of
Dfs. mal-10 and 17-25 (Fb), does not show mell; right from inclusion of AA-33.
bk 2: Between uncl and l(1)114 (fog). Left limit from inclusion of Q-456
(uncl); right, from non-inclusion of l(1)114
Df. With similar break points limits: 17-241
18.-Df(1)17-241
See above Df(1)14-11
19.-Df(1)17-196
Not covered by Dp(1;Y)BSYy+. Lethal with Df(1)B-111 and with lethals 114,
x-3, P-19, Q-463, x-4, R-9-18, 3-Des. Semi-lethal with Q-456. Viable with Dfs.
B-57, B-12, 16-3-35 (Fb), 17-25 (Fb), and lethals A-200, Q-56 (intro). Normal
with bbl.
bk1: Between l(1)Q-56 and uncl. Left limit from non-inclusion of l(1)Q-56;
right from inclusion of Q-456 (uncl)
bk2: Between su(f) and bb. Left limit from inclusion of 3-Des; right, normal
with bbl
Df. with similar break points limits: 17-408 (Fb)
20.-l(1)16-3-190
Not covered by the Dp(1;Y)BSYy+. Lethal with Df(1)B-111 and with lethal
114. Viable with Dfs. B-57, B-12, 16-3-3 (Fb), 17-25 (Fb), 17-123 (Fb),
16-1-80, 16-2-13 (Fb) and with lethals A-200, Q-56, Q-456, x-3, P-19, Q-463,
x-4, R-9-18, 3-Des. Normal with bbl.
Location: allele of l(1)114 (fog). l(1)16-3-190/Dp(1;Y)mal+ males are
sterile.
21.-l(1)16-2-27
Not covered by Dp(1;Y)BSYy+. Lethal with Dfs. B-12, 17-137 (Fb) and with
l(1)E-54. Viable with Dfs. B-111, B-57, 16-3-35 (Fb), 17-25 (Fb), 16-2-14,
17-351 (Fb) and with lethals A-112, LB 20, w-4, w-2, B-214, B-56, w-1, A-118,
R-9-28, E-81, AA-33.Shows eo with 17-36 (Fb).
Location: allele of l(1)E-54 (eo), isolated as lethal owing to the poor
viability of males.
Alleles: 16-3-119, 17-427, 17-260 (Fb), 17-36 (Fb), 14-1
22.-Df(1)19-18
Lethal with Dfs. B-111, B-57, B-12 and 16-3-35 (Fb) and with lethals A-200,
Q-56, Q-456, 114, x-3, P-19, Q-463, x-4, R-9-18, 3-Des, B-56, B-214, w-2, w-4,
LB20, 17-62, 14-1, 16-3-212, A-118, R-9-28, E-81, AA-33. Viable with Dfs.
17-25 and mal-10. Normal with ot. Lethal with bbl. Males
Df(1)19-18/Dp(1;Y)mal+ are sterile.
bk1: Between mell and leg. Left limit from non-inclusion of mell, viable with
Df(1)17-25; right from inclusion of l(1)AA-33
bk2: To the right of bb?, is lethal with bbl
Df. with similar break points: Df(1)16-3-129.- Df(1)16-3-129/Dp(1;Y)mal+
males are fertile.