FlyBase Gene Report: Dmel\intro

General Information

Symbol

Dmel\intro

Species

D. melanogaster

Name

introverted

Annotation Symbol

Feature Type

gene

FlyBase ID

FBgn0001268

Gene Model Status

Unannotated

Stock Availability

2 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Red Book
Interactive Fly

Also Known As

Q56, l(1)Q56, R9-13, YT1

Function

Gene Ontology (GO) Annotations (0 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

intro: introvert

Many mutants exhibit a pupal lethal phase, although some are larval lethals. [The name "introvert" is derived from abnormality of some hemizygous pupae in which the head remains inverted within the thorax (Schlosser et al.)]. Pupal-phase mutants do not contract at the beginning of pupation, remaining slender like larvae. Eye development very rudimentary. Germline clone analysis shows variable lethal phenotypes, including collapsed eggs (Perrimon et al.).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\intro using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\intro in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\intro

View exonic expression by tissue for Dmel\intro

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 19 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of intro

Transgenic constructs containing regulatory region of intro

Aberrations (Deficiencies and Duplications) ( 218 )

Inferred from experimentation ( 218 )

Gene not disrupted in

Df(1)2/19B

(Miklos and de Couet, 1990, Perrimon et al., 1989)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Miklos et al., 1987)

Df(1)16-3-35

(Munoz, 2004.1.5, Kramers et al., 1991, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)16-129

(Prud'homme et al., 1995, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)16-185

(Rahman and Lindsley, 1981)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)17-148

(Prud'homme et al., 1995, Perrimon et al., 1989, Rahman and Lindsley, 1981)

Df(1)17-196

(Munoz, 2003.12.10)

Df(1)17-257

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Schalet and Lefevre, 1973)

Df(1)17-351

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)17-401

(Munoz, 2004.1.5)

Df(1)17-408

(Rahman and Lindsley, 1981, Schalet and Lefevre, 1973)

Df(1)17-454

(Munoz, 2004.1.5)

Df(1)18-61

(Munoz, 2004.1.5)

Df(1)26B

(Perrimon et al., 1989)

Df(1)A53

(Perrimon et al., 1989)

Df(1)A58

(Lifschytz and Falk, 1969)

Df(1)A118

(Kramers et al., 1991, Perrimon et al., 1989, Miklos et al., 1987, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969)

Df(1)A209

(Zusman et al., 1985, Rahman and Lindsley, 1981, Lifschytz and Falk, 1969)

Df(1)B12

(Munoz, 2004.1.5, Prud'homme et al., 1995, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969)

Df(1)B56

(Lifschytz and Falk, 1969)

Df(1)B57

(Munoz, 2004.1.5, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1969)

Df(1)B214

(Lifschytz and Falk, 1969)

Df(1)EA113

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)fog-1

(Munoz, 2004.1.5)

Df(1)GA37

(Perrimon et al., 1989)

Df(1)GA42

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)GA90

(Zusman et al., 1985, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)GA104

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)GA131

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)GE263

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HC279

(Perrimon et al., 1989)

Df(1)HF359

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HM5

(Kramers et al., 1983)

Df(1)HM8

(Kramers et al., 1983)

Df(1)HM44

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)HM47

(Kramers et al., 1983)

Df(1)HM49

(Kramers et al., 1983)

Df(1)HM50

(Kramers et al., 1983)

Df(1)HM407

(Kramers et al., 1983)

Df(1)HM430

(Perrimon et al., 1989, Kramers et al., 1983)

Df(1)HM444

(Kramers et al., 1983)

Df(1)JA21

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)JA117

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)JC77

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)K5

(Rahman and Lindsley, 1981)

Df(1)LB6

(Prud'homme et al., 1995, Perrimon et al., 1989, Schalet and Lefevre, 1973)

Df(1)M31

(Lifschytz and Yakobovitz, 1978)

Df(1)M158

(Lifschytz and Yakobovitz, 1978)

Df(1)M171

(Lifschytz and Yakobovitz, 1978)

Df(1)M176

(Lifschytz and Yakobovitz, 1978)

Df(1)mal6

(Kramers et al., 1991, Kramers et al., 1983, Schalet and Lefevre, 1973)

Df(1)mal8

(Kramers et al., 1991, Zusman et al., 1985)

Df(1)mal10

(Perrimon et al., 1989)

Df(1)mal17

(Perrimon et al., 1989)

Df(1)Q38

(Lifschytz and Falk, 1969)

Df(1)Q539

(Prud'homme et al., 1995, Kramers et al., 1991, Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987, Zusman et al., 1985, Kramers et al., 1983, Lifschytz and Falk, 1969)

Df(1)R2

(Rahman and Lindsley, 1981)

Df(1)R6

(Rahman and Lindsley, 1981)

Df(1)R7

(Rahman and Lindsley, 1981)

Df(1)R8A

(Rahman and Lindsley, 1981)

Df(1)R8

(Rahman and Lindsley, 1981)

Df(1)R-9-1

(Lifschytz and Falk, 1969)

Df(1)R10

(Rahman and Lindsley, 1981)

Df(1)R12

(Rahman and Lindsley, 1981)

Df(1)R16

(Rahman and Lindsley, 1981)

Df(1)R17

(Rahman and Lindsley, 1981)

Df(1)R18

(Rahman and Lindsley, 1981)

Df(1)R23

(Rahman and Lindsley, 1981)

Df(1)R25

(Rahman and Lindsley, 1981)

Df(1)R26

(Rahman and Lindsley, 1981)

Df(1)R30

(Rahman and Lindsley, 1981)

Df(1)R36

(Rahman and Lindsley, 1981)

Df(1)R42

(Rahman and Lindsley, 1981)

Df(1)R43

(Rahman and Lindsley, 1981)

Df(1)R46

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)run1112

(Perrimon et al., 1989, Zusman et al., 1985)

Df(1)S54

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)su(f)724

(Prud'homme et al., 1995, Lifschytz and Yakobovitz, 1978)

Df(1)su(f)733

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)795

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)7009

(Lifschytz and Yakobovitz, 1978)

Df(1)T2-14A

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)X-1

(Rahman and Lindsley, 1981, Rahman and Lindsley, 1980, Lifschytz and Falk, 1969)

Df(1)yl-1

(Lifschytz and Falk, 1969)

Df(1)y-X5

(Rahman and Lindsley, 1981)

Df(1)y-X15

(Kramers et al., 1991, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Dp(1;Y)su(f)^-

Gene disrupted in

Df(1)13C3

(Schalet and Lefevre, 1973)

Df(1)14-11

(Munoz, 2003.12.10)

Df(1)15-13

(Munoz, 2003.12.10)

Df(1)16-1-80

(Munoz, 2003.12.10)

Df(1)16-1-88

(Munoz, 2004.1.5)

Df(1)16-2-13

(Prud'homme et al., 1995, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)16-3-20

(Munoz, 2003.12.10)

Df(1)16-3-34

(Munoz, 2004.1.5, Munoz, 2003.12.10)

Df(1)16-3-93

(Munoz, 2003.12.10)

Df(1)16-3-139

(Munoz, 2004.1.5)

Df(1)16-3-211

(Munoz, 2003.12.10)

Df(1)17-137

(Kramers et al., 1991, Perrimon et al., 1989, Rahman and Lindsley, 1981)

Df(1)17-228

(Munoz, 2004.1.5)

Df(1)17-241

(Munoz, 2003.12.10)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Schalet and Lefevre, 1973)

Df(1)17-466

(Schalet and Lefevre, 1973)

Df(1)17-489

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)18-6

(Munoz, 2003.12.10)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2004.1.5)

(Munoz, 2003.12.10)

Df(1)A19

(Lifschytz and Falk, 1969)

Df(1)A33

(Lifschytz and Falk, 1969)

Df(1)A122

(Schalet and Lefevre, 1973, Lifschytz and Falk, 1969)

Df(1)A209

(Rahman and Lindsley, 1980)

Df(1)B82

(Lifschytz and Falk, 1969)

Df(1)B111

(Munoz, 2004.1.5, Lifschytz and Falk, 1969)

Df(1)B155

(Lifschytz and Falk, 1969)

Df(1)B264

(Lifschytz and Falk, 1969)

Df(1)C74

(Miklos and de Couet, 1990, Perrimon et al., 1989)

Df(1)D43L1

(Kramers et al., 1991, Perrimon et al., 1989, Kramers et al., 1983, Rahman and Lindsley, 1981, Schalet and Lefevre, 1973)

Df(1)DCB1-35b

(Prud'homme et al., 1995, Perrimon et al., 1989, Zusman et al., 1985, Schalet and Lefevre, 1973)

Df(1)DCB1-35c

(Prud'homme et al., 1995, Perrimon et al., 1989, Miklos et al., 1987, Schalet and Lefevre, 1973)

Df(1)flam-l9

(Prud'homme et al., 1995)

Df(1)GA22

(Perrimon et al., 1989, Miklos et al., 1987)

Df(1)GA33

(Perrimon et al., 1989)

Df(1)GA40

(Perrimon et al., 1989)

Df(1)HM45

(Kramers et al., 1983)

Df(1)HM418

(Kramers et al., 1983)

Df(1)HM422

(Kramers et al., 1983)

Df(1)HM455

(Kramers et al., 1983)

Df(1)JC4

(Miklos and de Couet, 1990, Perrimon et al., 1989, Miklos et al., 1987)

Df(1)JC12

(Perrimon et al., 1989)

Df(1)l2

(Prud'homme et al., 1995)

Df(1)l3

(Prud'homme et al., 1995)

Df(1)l4

(Prud'homme et al., 1995)

Df(1)l5

(Prud'homme et al., 1995)

Df(1)l6

(Prud'homme et al., 1995)

Df(1)l7

(Prud'homme et al., 1995)

Df(1)l8

(Prud'homme et al., 1995)

Df(1)l12

(Prud'homme et al., 1995)

Df(1)l13

(Prud'homme et al., 1995)

Df(1)l14

(Prud'homme et al., 1995)

Df(1)l15

(Prud'homme et al., 1995)

Df(1)LB7

(Perrimon et al., 1989)

Df(1)LB23

(Perrimon et al., 1989, Schalet and Lefevre, 1973)

Df(1)mal3

(Kramers et al., 1991, Kramers et al., 1983, Rahman and Lindsley, 1981)

Df(1)mal12

(Zusman et al., 1985, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)n17-8

(Munoz, 2004.1.5)

Df(1)N77

(Perrimon et al., 1989)

Df(1)Q219

(Lifschytz and Falk, 1969)

Df(1)Q408

(Lifschytz and Falk, 1969)

Df(1)R1

(Rahman and Lindsley, 1981)

Df(1)R3

(Rahman and Lindsley, 1981)

Df(1)R4

(Rahman and Lindsley, 1981)

Df(1)R5

(Rahman and Lindsley, 1981)

Df(1)R9

(Rahman and Lindsley, 1981)

Df(1)R-10-5

(Lifschytz and Falk, 1969)

Df(1)R11

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R13

(Rahman and Lindsley, 1981)

Df(1)R14

(Rahman and Lindsley, 1981)

Df(1)R15

(Rahman and Lindsley, 1981)

Df(1)R19

(Rahman and Lindsley, 1981)

Df(1)R20

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R21

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R22

(Prud'homme et al., 1995, Rahman and Lindsley, 1981)

Df(1)R24

(Rahman and Lindsley, 1981)

Df(1)R25

(Rahman and Lindsley, 1980)

Df(1)R27

(Rahman and Lindsley, 1981)

Df(1)R28

(Rahman and Lindsley, 1981)

Df(1)R29

(Rahman and Lindsley, 1981)

Df(1)R31

(Rahman and Lindsley, 1981)

Df(1)R32

(Rahman and Lindsley, 1981)

Df(1)R33

(Rahman and Lindsley, 1981)

Df(1)R34

(Rahman and Lindsley, 1981)

Df(1)R35

(Rahman and Lindsley, 1981)

Df(1)R37

(Rahman and Lindsley, 1981)

Df(1)R38

(Rahman and Lindsley, 1981)

Df(1)R39

(Rahman and Lindsley, 1981)

Df(1)R40

(Rahman and Lindsley, 1981)

Df(1)R41

(Rahman and Lindsley, 1981)

Df(1)R44

(Prud'homme et al., 1995, Rahman and Lindsley, 1981, Rahman and Lindsley, 1980)

Df(1)R45

(Rahman and Lindsley, 1981)

Df(1)R47

(Rahman and Lindsley, 1981)

Df(1)R48

(Rahman and Lindsley, 1981)

Df(1)Sp20A-F

(Schalet, 1986)

Df(1)su(f)4B

(Kramers et al., 1991, Kramers et al., 1983)

Df(1)su(f)754

(Lifschytz and Yakobovitz, 1978)

Df(1)su(f)⁵

(Schalet and Lefevre, 1973)

Df(1)wl-2

(Lifschytz and Falk, 1969)

Dp(1;Y)y⁺mal¹²⁶

(Lifschytz and Yakobovitz, 1978)

Gene not duplicated in

Dp(1;Y)Bar^S

(Prud'homme et al., 1995, Kramers et al., 1991, Perrimon et al., 1989, Kramers et al., 1983)

Dp(1;Y)Bar^SYy⁺

(Munoz, 2004.1.5, Rahman and Lindsley, 1981)

Dp(1;Y)y⁺mal¹¹⁸

(Prud'homme et al., 1995)

Dp(1;Y)y⁺mal^N152

(Prud'homme et al., 1995)

Gene duplicated in

Dp(1;f)3

(Perrimon et al., 1989, Rahman and Lindsley, 1981)

Dp(1;f)mini2

(Prud'homme et al., 1995, Perrimon et al., 1989)

Dp(1;f)mini6

(Prud'homme et al., 1995, Perrimon et al., 1989)

Dp(1;f)mini7

(Prud'homme et al., 1995)

Dp(1;f)mini77

(Miklos and de Couet, 1990, Perrimon et al., 1989)

Dp(1;f)mini-ring

(Perrimon et al., 1989)

Dp(1;Y)B101

(Perrimon et al., 1989)

Dp(1;Y)mal⁺

(Rahman and Lindsley, 1981)

Dp(1;Y)y⁺mal¹⁰²

(Prud'homme et al., 1995, Perrimon et al., 1989)

Dp(1;Y)y⁺mal¹⁰⁶

(Prud'homme et al., 1995, Miklos and de Couet, 1990)

Dp(1;Y)y⁺mal¹⁰⁸

(Schalet and Lefevre, 1973)

Dp(1;Y)y⁺mal¹²⁶

(Prud'homme et al., 1995, Kramers et al., 1991, Miklos and de Couet, 1990, Perrimon et al., 1989, Kramers et al., 1983, Rahman and Lindsley, 1981, Schalet and Lefevre, 1973)

Dp(1;Y)y⁺mal¹⁷¹

(Perrimon et al., 1989)

Dp(1;Y)y⁺mal⁺

(Prud'homme et al., 1995, Lefevre, 1981)

Ts(1Rt;YLt)B108

(Perrimon et al., 1989)

Ts(1Rt;YLt)B109

(Perrimon et al., 1989)

Ts(1Rt;YLt)B154

(Perrimon et al., 1989)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal (with Dp(1;3)DC386)

intro³

lethal (with Dp(1;3)DC387)

intro³

lethal (with Dp(1;3)DC388)

intro³

lethal (with Dp(1;3)DC390)

intro³

lethal (with Dp(1;3)DC562)

intro³

lethal | recessive

lethal - all die before end of larval stage | recessive

intro⁹

lethal - all die before end of pupal stage | recessive

viable (with Dp(1;3)DC389)

intro³

Other Phenotypes

Allele

some die during larval stage | recessive

intro⁹

some die during pupal stage | recessive

Phenotype manifest in

Allele

head

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (0)

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (0)

Mus musculus (laboratory mouse) (0)

Xenopus tropicalis (Western clawed frog) (0)

Danio rerio (Zebrafish) (0)

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (0)

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:intro. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-[66]

Cytogenetic map

20A3-20A4

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

20A3-20A4

Left limit from inclusion within Df(1)Sp20A-F (FBrf0045066) Right limit from inclusion within Df(1)mal3 (FBrf0036523)

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-[66]

Left of (cM)

(Schalet, 1972)

Right of (cM)

(Schalet, 1972)

Notes

Stocks and Reagents

Stocks (2)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

intro³/FM6/Dp(1;Y)mal⁺

Kyoto

105706

intro³/FM6/Dp(1;Y)mal⁺

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Many mutants exhibit a pupal lethal phase, although some are larval lethals. Pupal-phase mutants do not contract at the beginning of pupation, remaining slender like larvae. Eye development very rudimentary. Germline clone analysis shows variable lethal phenotypes, including collapsed eggs (Perrimon et al.).

Relationship to Other Genes

Source for database merge of

Additional comments

Complementation mapping and RNAi knockdown data suggests that intro corresponds to CG14619, although the possibility of off-target effects means that this assertion is only tentative and further experiments are required to confirm this.

(Morriss et al., 2013)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

The name 'introvert' is derived from abnormality of some hemizygous pupae in which the head remains inverted within the thorax (Schlosser et al., 1992).

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

(Lifschytz and Falk, 1969)

Q56

(Kramers et al., 1991, Perrimon et al., 1989, Lefevre and Watkins, 1986, Schalet, 1986, Kramers et al., 1983, Lefevre, 1981, Rahman and Lindsley, 1981)

R9-13

(Bergman et al., 2006, Lifschytz, 1978)

YT1

(Bergman et al., 2006, Lifschytz, 1978)

intro

(Morriss et al., 2013, Lindsley and Zimm, 1992)

l(1)19-88

l(1)20Ac

l(1)Q56

(Miklos et al., 1987, Rahman and Lindsley, 1980, Schalet, 1972)

Name Synonyms

introvert

(Lindsley and Zimm, 1992)

introverted

(Morriss et al., 2013)

section 23

(Lifschytz and Falk, 1969)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (27)

NA

Report Sections