mir-iab-4-5p, miR-iab4, iab-4, iab-4-5p, dme-miR-iab-4
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mir-iab-4 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mir-iab-4 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: mir-iab-4-5p mir-iab-4-3p
The annotation for mir-iab-4 has been changed in release 5.31 of the genome annotation, so that instead of representing a mature miRNA it now represents the precursor stem loop pre-miRNA. Thus the separate annotations (CR33624 and CR33623) which previously each represented one of the two mature miRNAs made from the mir-iab-4 stem loop precursor have been converted into a single annotation (CR43043).
The "iab-8" non-coding transcript encodes a microRNA (represented by "mir-iab-8") derived from a hairpin which is complementary to the hairpin present in the "iab-4" non-coding transcript (the hairpin in the "iab-4" transcript is represented by "mir-iab-4").
The "mir-iab-4" and "mir-iab-8" precursor hairpins are encoded on opposite strands of the same genomic region. The mature miRNAs derived from each hairpin have very similar sequences, but are shifted by 2 nucleotides at the 5' end and also differ in four positions at the 3' region.
The "mir-iab-4" and "mir-iab-8" precursor hairpins are encoded on opposite strands of the same genomic region. The major products of both hairpins are their respective "5p" species. While the 5' ends of the mature microRNA from each hairpin (mir-iab-4-5p and mir-iab-8-5p respectively) are related, the mir-iab-8-5p microRNA contains a strict 2 nucleotide "UU" extension.
The "iab-4" locus produces two microRNAs, represented by "mir-iab-4".
New annotation (CR33624) in release 4.1 of the genome annotation.
New annotation (CR33623) in release 4.1 of the genome annotation.
Ectopic expression of the mir-iab-4 microRNAs induces a classical homeotic mutant phenotype; the transformation of halteres into wings.