MBD-like, MTA1-like and Mi-2 proteins copurify in ion exchange chromatography and further co-elute on a gel filtration column with an apparent molecular mass of about 1 MDa.

Proteins endogenous to nuclear extract.

Nuclear extract was fractionated by ion exchange chromatography, and the MBD-like-containing fraction was subjected to molecular sieving by gel filtration chromatography.

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

MBD-like-PA and MBD-like-PB