FB2021_02, released April 13, 2021

Physical Interaction report

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General Information
Interaction Type
physical association
Interacting Genes
Mer, Sik2
FlyBase ID
FBig0000097108
Interaction Network
Interactions Browser links
Mer network
Sik2 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0220751-6.coIP.WB
Reference
Wehr et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
Mer 

Mer

bait

FLAG tag

Sik2 

Sik2

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Wehr et al., 2013)

Sik2 interacts with sav and to a lesser extent with Mer (in a sav-dependent manner), but not other components of the signaling pathway (hpo or wts).

(Wehr et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)