FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
AGO1, mir-277
FlyBase ID
FBig0000098644
Interaction Network
Interactions Browser links
AGO1 network
mir-277 network
Reported Interactions
FBrf0200521-1.coIP.NB
Reference
Förstemann et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
AGO1 

AGO1

bait
mir-277 

miR-277

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Only about a third of mir-277 coimmunoprecipitates with AGO1; most remains unbound. This is consistent with functional studies suggesting that AGO1 and AGO2 compete for binding to mir-277.

(Förstemann et al., 2007)

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Förstemann et al., 2007)
FBrf0224072-2.coIP.NB
Reference
Yang et al., 2014
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
AGO1 

AGO1

bait

FLAG tag

mir-277 

mir-277

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yang et al., 2014)
External Crossreferences and Linkouts ( 0 )
References (2)