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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000098823
Interaction Network
Interactions Browser links
Lnk network
chico network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0210745-1.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Chico

bait

V5 tag

Lnk 

dSH2B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Coexpression of Lnk with chico enhances insulin-induced tyrosine phosphorylation of chico.

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

FBrf0221426-2.FRET
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Lnk 

Lnk

bait

CFP tag

Chico

prey

RFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The Lnk-chico interaction is observed in 73% of samples upon insulin stimulation of tissue (compared to 30% of samples in the absence of insulin).

Source was larval salivary gland of transgenic fly line; bait produced from tagged transgenic construct; prey produced from tagged transgenic construct.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)