FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Rho1, Fhos
FlyBase ID
FBig0000102417
Interaction Network
Interactions Browser links
Rho1 network
Fhos network
Reported Interactions
FBrf0224315-2.PD.WB
Reference
Lammel et al., 2014
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
Rho1 

RhoA

bait

GST tag

Fhos 

Fhos

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from S2 cell extract.

(Lammel et al., 2014)

Binding of Fhos to Rho1 is independent of the presence of GDP or GTPĪ³S.

(Lammel et al., 2014)

Fhos also binds to Rac1 but not Cdc42.

(Lammel et al., 2014)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)