FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
slmb, Cap-H2
FlyBase ID
FBig0000102581
Interaction Network
Interactions Browser links
slmb network
Cap-H2 network
Reported Interactions
FBrf0221230-1.coIP.WB
Reference
Buster et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Cap-H2 

Cap-H2

bait

EGFP tag

Cap-H2 
slmb 

Slimb

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Cap-H2 
Slimb binding region
necessary binding region
TPSDADSGISSMGSSLASTARLK

last 23 residues of Cap-H2

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Buster et al., 2013)

Mutation of the slmb binding region results in a massive increase in Cap-H2 protein accumulation.

(Buster et al., 2013)
FBrf0221230-3.coIP.WB
Reference
Buster et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
slmb 

Slimb

bait
Cap-H2 

Cap-H2

prey

EGFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from transfected construct.

(Buster et al., 2013)
FBrf0227673-1.coIP.WB
Reference
Nguyen et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
Cap-H2 

Cap-H2

bait

GFP tag

slmb 

Slimb

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Kc167; bait produced from transfected construct; prey produced from endogenous gene.

(Nguyen et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)