FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Panx, piwi
FlyBase ID
FBig0000103724
Interaction Network
Interactions Browser links
Panx network
piwi network
Reported Interactions
FBrf0229930-1.coIP.WB
Reference
Yu et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSS
Participants
Corresponds to
Reported as
Role
Note
piwi 

Piwi

bait

GFP tag

Panx 

CG9754

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSS cell line; bait produced from transfected construct; prey produced from transfected construct.

(Yu et al., 2015)
FBrf0229930-2.coIP.WB
Reference
Yu et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSS
Participants
Corresponds to
Reported as
Role
Note
Panx 

CG9754

bait

FLAG tag

piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSS cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Yu et al., 2015)
FBrf0230020-1.coIP.WB
Reference
Sienski et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
piwi 

Piwi

bait
Panx 

CG9754

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Sienski et al., 2015)
FBrf0230020-2.coIP.WB
Reference
Sienski et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
Panx 

CG9754-XP

bait
piwi 

Piwi-XP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Sienski et al., 2015)
FBrf0243113-8.coIP.WB
Reference
Fabry et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
Panx 

Panx

bait

FLAG tag

piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSC cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Fabry et al., 2019)

Interaction is weak.

(Fabry et al., 2019)
FBrf0243162-6.coIP.WB
Reference
Batki et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
Panx 

Panoramix

bait
piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Batki et al., 2019)
FBrf0243284-10.coIP.WB
Reference
Murano et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
piwi 

Piwi

bait
Panx 

Panx

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Murano et al., 2019)
FBrf0243284-2.coIP.WB
Reference
Murano et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
Panx 

Panx

bait

GFP tag

Panx 
Panx 
piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Panx 
N-terminal domain
sufficient binding region
aa 1-299

coordinates relative to Panx-PA

Panx 
N-terminal domain
necessary binding region
aa 1-169

coordinates relative to Panx-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSC cell line; bait produced from endogenous gene or transfected construct; prey produced from endogenous gene.

(Murano et al., 2019)
FBrf0243284-6.coIP.WB
Reference
Murano et al., 2019
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Panx 

Panx

bait
piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Murano et al., 2019)
FBrf0243284-9.coIP.MS
Reference
Murano et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
Panx 

Panx

bait
piwi 

Piwi

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Murano et al., 2019)
FBrf0247529-2.coIP.WB
Reference
Onishi et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
piwi 

Piwi

bait
Panx 

Panx

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Onishi et al., 2020)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (6)