FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Ptp69D, Dscam1
FlyBase ID
FBig0000103959
Interaction Network
Interactions Browser links
Ptp69D network
Dscam1 network
Reported Interactions
FBrf0229399-1.coIP.WB
Reference
Dascenco et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Ptp69D 

RPTP69D

bait

HA

Dscam1 

Dscam1

prey
Dscam1 
Dscam1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dscam1 
interaction domain 1
mutation increasing interaction

Mutations in the WPD loop of domain 1

Dscam1 
interaction domain 2
mutation increasing interaction

Mutations in the WPD loop of domain 2

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Dascenco et al., 2015)

Mutations in the WPD loop of either domain 1 or domain 2 of Dscam1 are necessary for the interaction.

(Dascenco et al., 2015)
FBrf0229399-2.coIP.WB
Reference
Dascenco et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Ptp69D 

RPTP69D

bait

V5

Dscam1 

Dscam1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Use of sli conditioned media increased interaction between Ptp69D and Dscam1.

(Dascenco et al., 2015)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Dascenco et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)