FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Pten, baz
FlyBase ID
FBig0000104023
Interaction Network
Interactions Browser links
Pten network
baz network
Reported Interactions
FBrf0183928-1.Y2H
Reference
von Stein et al., 2005
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
baz 

Baz

bait

fused to GAL4 DNA-binding domain

baz 
Pten 

PTEN

prey

fused to GAL4 activation domain

Pten 
Pten 
Pten 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
baz 
PDZ domains 2-3
sufficient binding region
aa 401-737
Pten 
C-terminal PDZ-binding motif
sufficient binding region
aa 316-511
Pten 
C-terminal PDZ-binding motif
necessary binding region
aa 297-508
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(von Stein et al., 2005)

Pten isoform PC did not interact with baz in this assay.

(von Stein et al., 2005)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from embryo cDNA expression library).

(von Stein et al., 2005)
FBrf0183928-2.coIP.WB
Reference
von Stein et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
baz 

Baz

bait
Pten 

PTEN

prey
Pten 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(von Stein et al., 2005)

Pten isoform PC did not interact with baz in this assay.

(von Stein et al., 2005)
FBrf0183928-3.coIP.WB
Reference
von Stein et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Pten 

PTEN

bait
Pten 
baz 

Baz

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(von Stein et al., 2005)

Pten isoform PC did not interact with baz in this assay.

(von Stein et al., 2005)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)