FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
DCP1, Ge-1
FlyBase ID
FBig0000104091
Interaction Network
Interactions Browser links
DCP1 network
Ge-1 network
Reported Interactions
FBrf0206975-2.coIP.WB
Reference
Jinek et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Ge-1 

Ge-1

bait

HA tag

DCP1 

DCP1

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Jinek et al., 2008)
FBrf0220119-9.coIP.WB
Reference
Braun et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
DCP1 

DCP1

bait

GFP tag

Ge-1 

EDC4

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Disruption of the Dcp1-pcm interaction by the Dcp1 Y34A mutation does not disrupt Dcp1-Dcp2 or Dcp1-Ge-1 interactions.

(Braun et al., 2012)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Braun et al., 2012)
FBrf0234688-10.coIP.WB
Reference
Sgromo et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-ATCC
Participants
Corresponds to
Reported as
Role
Note
DCP1 

DCP1

bait

GFP tag

Ge-1 

EDC4

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Sgromo et al., 2017)

Positive control.

(Sgromo et al., 2017)
FBrf0245433-2.coIP.WB
Reference
Lee et al., 2020
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ge-1 

dGe-1

bait

V5 tag

DCP1 

dDcp1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Lee et al., 2020)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (4)