FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mei-P26, AGO1
FlyBase ID
FBig0000104306
Interaction Network
Interactions Browser links
mei-P26 network
AGO1 network
Reported Interactions
FBrf0206272-4.coIP.WB
Reference
Neumuller et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mei-P26 

Mei-P26

bait

GFP tag

mei-P26 
AGO1 

AGO1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mei-P26 
NHL domain
necessary binding region
aa 1-933
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Neumuller et al., 2008)
FBrf0218009-1.coIP.WB
Reference
Li et al., 2012
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mei-P26 

mei-P26

bait
AGO1 

AGO1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of wild-type or transgenic fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Li et al., 2012)

Interaction detected in wild-type and dpp overexpressing ovaries.

(Li et al., 2012)
FBrf0218009-2.coIP.WB
Reference
Li et al., 2012
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO1 

AGO1

bait
mei-P26 

mei-P26

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of wild-type or mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Li et al., 2012)

Interaction detected in wild-type and bam mutant ovaries.

(Li et al., 2012)
FBrf0237766-16.BiFC.FM
Reference
Malik et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO1 

Ago-1

unspecified role

GFP tag, fragment unspecified

AGO1 

Ago-1

unspecified role

GFP tag, fragment unspecified

AGO1 

Ago-1

unspecified role

GFP tag, fragment unspecified

mei-P26 

Mei-P26

unspecified role

GFP tag, fragment unspecified

mei-P26 

Mei-P26

unspecified role

GFP tag, fragment unspecified

mei-P26 

Mei-P26

unspecified role

GFP tag, fragment unspecified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was live HEK293T cells; proteins produced from transfected constructs.

(Malik et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)