FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Dredd
FlyBase ID
FBig0000104843
Interaction Network
Interactions Browser links
Dredd network
Reported Interactions
FBrf0218688-8.coIP.WB
Reference
Meinander et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Dredd 

Dredd

bait

V5 tag

Dredd 

Dredd

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Meinander et al., 2012)
FBrf0225647-3.ENZ.WB
Reference
Kim et al., 2014
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dredd 

Dredd

self

FLAG tag

Dredd 

Dredd

self

FLAG tag

Dredd 
Dredd 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dredd 
catalytic domain residue 408
mutation disrupting interaction
aa 408

C408A

Dredd 
interdomain cleavage site
mutation disrupting interaction
aa 436

D436A (not D436N)

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; enzyme purified from transfected S2 cell extract; enzyme target purified from transfected S2 cell extract.

(Kim et al., 2014)

Dredd cleaves itself.

(Kim et al., 2014)
External Crossreferences and Linkouts ( 0 )
References (2)