FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
lft, ds
FlyBase ID
FBig0000104930
Interaction Network
Interactions Browser links
lft network
ds network
Reported Interactions
FBrf0209094-2.coIP.WB
Reference
Mao et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
lft 

Lft

bait

FLAG tag

ds 

Ds

prey

V5 tag

ds 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
ds 
intracellular plus transmembrane domains
unspecified role

\'Ds-TM-ICD\'

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line transfected with tagged lft and ds constructs.

(Mao et al., 2009)
FBrf0260993-1.coIP.WB
Reference
Tripathi and Irvine, 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
ds 

ds

bait

V5 tag

ds 
lft 

lft

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
ds 
intracellular D II and III motif
necessary binding region
aa 246-292

coordinates relative to ds-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Tripathi and Irvine, 2024)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)