FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
AGO1, Hsc70-4
FlyBase ID
FBig0000115846
Interaction Network
Interactions Browser links
AGO1 network
Hsc70-4 network
Reported Interactions
FBrf0214214-1.PD.WB
Reference
Iwasaki et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Hsc70-4 

Hsc70-4

bait

SBP tag

AGO1 

Ago1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Iwasaki et al., 2010)

Treatment with PES, an Hsp70 inhibitor, decreases the Hsc70-4-AGO1 interaction.

(Iwasaki et al., 2010)
FBrf0214214-3.coIP.MS
Reference
Iwasaki et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
AGO1 

Ago1

bait

FLAG tag

Hsc70-4 

Hsc70-4

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Iwasaki et al., 2010)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)