FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Kr-h1, foxo
FlyBase ID
FBig0000116143
Interaction Network
Interactions Browser links
Kr-h1 network
foxo network
Reported Interactions
FBrf0237385-1.coIP.WB
Reference
Kang et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
foxo 

dFOXO

bait
Kr-h1 

Kr-h1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of Kc167 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Kang et al., 2017)
FBrf0237385-2.coIP.WB
Reference
Kang et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
Kr-h1 

Kr-h1

bait

FLAG tag

Kr-h1 
Kr-h1 
foxo 

dFOXO

prey

HA tag

foxo 
foxo 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
foxo 
DNA binding domain
sufficient binding region
aa 1-262

coordinates relative to foxo-PF

foxo 
trans activation domain
sufficient binding region
aa 262-622

coordinates relative to foxo-PF

Kr-h1 
Q-rich domain
sufficient binding region
aa 1-140

coordinates relative to Kr-h1-PA

Kr-h1 
Q-rich domain
necessary binding region
aa 1-140

coordinates relative to Kr-h1-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of Kc167 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Kang et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)