Kr-h, Pow, Passion of white, l(2)10642
Gene model reviewed during 5.54
The 3.8 kb Kr-h1 transcript is present at low levels in 0-4 hr embryos and at high levels in mid-embryogenesis. Levels subsequently decline.
Low levels of the 4.5 kb Kr-h1 transcripts are present in mid-embryogenesis and also in first instar larvae. Expression levels become significant starting at second larval instar and continue through 6-8 hours after pupariation. The transcript is also present in adult flies.
None of the polypeptides share 100% sequence identity.
845, 791 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Kr-h1 using the Feature Mapper tool.
Comment: reported as posterior spiracle specific anlage
GBrowse - Visual display of RNA-Seq signalsView Dmel\Kr-h1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Annotation CG18783 split into CG45074 (Kr-h1) and CG45075 in release 5.54 of the genome annotation. Split based on cDNA, EST and RNA-Seq data.
One or more of the processed transcripts for these genes contain two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG45074 (Kr-h1) and CG45075.
Source for merge of Kr-h1 CG18783 was a shared cDNA ( date:010720 ).
Ortholog of B. mori juvenile-hormone-related gene (involved in JH biosynthesis, metabolism or signaling).
Kr-h1 acts as a modulator of the expression of many ecdysone regulated genes during metamorphosis.
A 4.5kb transcript of Kr-h1 is indispensable for normal progression of metamorphosis.
Identified as a dosage sensitive modifier of w allele expression.
Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.