FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
slmb, Set8
FlyBase ID
FBig0000116418
Interaction Network
Interactions Browser links
slmb network
Set8 network
Reported Interactions
FBrf0238636-1.coIP.WB
Reference
Zouaz et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Set8 

PR-Set7

bait

FLAG tag

slmb 

Slimb

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Zouaz et al., 2018)
FBrf0238636-2.coIP.WB
Reference
Zouaz et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
slmb 

Slimb

bait

FLAG tag

Set8 

PR-Set7

prey

GFP tag

Set8 
Set8 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Set8 
C-terminal domain
sufficient binding region
aa 500-691
Set8 
SET domain residue 634
mutation disrupting interaction
aa 634

R634P

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zouaz et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)