FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
yki, Pax
FlyBase ID
FBig0000123487
Interaction Network
Interactions Browser links
yki network
Pax network
Reported Interactions
FBrf0261383-1.coIP.WB
Reference
Jiang et al., 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
yki 

yki

bait

Myc tag

yki 
Pax 

Pax

prey

FLAG tag

Pax 
Pax 
Pax 
Pax 
Pax 
Pax 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Pax 
N-terminal domain
sufficient binding region
aa 1-341
Pax 
N-terminal leucine-rich domain 1
necessary binding region
aa 25-38
Pax 
N-terminal leucine-rich domain 2
necessary binding region
aa 127-140
Pax 
N-terminal leucine-rich domain 3
necessary binding region
aa 165-178
Pax 
N-terminal leucine-rich domain 4
necessary binding region
aa 251-264
Pax 
N-terminal leucine-rich domain 5
necessary binding region
aa 321-334
yki 
N-terminal domain
sufficient binding region
aa 1-194
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Jiang et al., 2025)
FBrf0261383-2.coIP.WB
Reference
Jiang et al., 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Pax 

Pax

bait
yki 

yki

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait and prey produced from endogenous genes.

(Jiang et al., 2025)
External Crossreferences and Linkouts ( 0 )
References (1)