Shvartsman, P.I., Isaenko, O.A. (1999). [Frequency of embryonal lethality in various strains of Drosophila melanogaster under conditions of destabilization of microtubule apparatus and as affected by heat shock.]  Genetika, Moscow 35(5): 712--715.

FBrf0112037

Research paper

Efficiency of heat shock and three compounds belonging to a group of mitotic poisons (colchicine (Cl), griseofulvin (Gf) and vinblastine (Vb)) in induction of dominant lethal mutations (DLM) in the Canton S wild type strain and the l(l)ts403 temperature-sensitive strain was shown. The mutagen-sensitive strain, mus(2)201Gl, displays no sensitivity to these drugs according to the DLM criterion. Heat shock followed by the Vb and Gf treatment leads to a reduction in the frequencies of DLM. Conversely, a combination of Cl with heat shock increases the yield of DLM.