Subject: Helping FlyBase: ADRC-10294 Dear Scott, We are currently curating the abstracts for the upcoming 45th (Washington DC) Annual Drosophila Research Conference, for FlyBase. I am writing in connection with your abstract: A role for Kinesin-like protein 3A (Klp3A) in regulating meiotic exchanges is implicated by identification of the mei-352 mutation. At FlyBase we would merge the gene record for Klp3A with that for mei-352 if we were confident that the two records represent the same gene in reality. You wrote \- 'These results strongly indicate that klp3A is the gene responsible for the mei-352 mutant' \- and I'm wondering if by now the last vestige of reservation is gone and we can go ahead and merge these records. The evidence in the abstract looks promising ... The new name for the merged gene record would be Klp3A with mei-352 relegated to a synonym. With best wishes, Rachel. \---------------------------------------------------------------------- Rachel Drysdale, Ph.D. FlyBase (Cambridge), \---------------------------------------------------------------------- Subject: RE: Helping FlyBase: ADRC-10294 Rachel, I am confident that mei-352 is an allele of Klp3A. Klp3A alleles 521 and 63e4 fail to complement mei-352 (other alleles have not yet been tested), and mei-352 bears a missense point mutation in a conserved residue of Klp3A. Sorry for the delay, Scott \++++++++++++++++++++++++++++++++++++++ Scott L. Page, Ph.D. Stowers Institute for Medical Research 1000 E. 50th Street Kansas City, MO 64110
