Lattao, R., Bonaccorsi, S., Guan, X., Wasserman, S.S., Gatti, M. (2011). Tubby-tagged balancers for the Drosophila X and second chromosomes. Fly 5(4): 369--370.
FlyBase ID
FBrf0216878
Publication Type
Research paper
Abstract
We generated FM7a and CyO balancer chromosomes bearing a Tubby1 (Tb1) dominant transgene. Flies heterozygous for these FM7a and CyO derivatives exhibit a phenotype undistinguishable from that elicited by the Tb1 mutation associated with the TM6B balancer. We tested two of these Tb-bearing balancers (FM7-TbA and CyO-TbA) for more than 30 generations and found that the Tb1 transgene they carry is stable. Thus, these new Tb-tagged balancers are particularly useful for balancing lethal mutations and distinguish homozygous mutant larvae from their heterozygous siblings.
