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Citation
Shcherbata, H.R. (2019). miRNA functions in stem cells and their niches: lessons from the Drosophila ovary.  Curr. Opin. Insect Sci. 31(): 29--36.
FlyBase ID
FBrf0242423
Publication Type
Review
Abstract

From the very beginning of the miRNA era, Drosophila has served as an excellent model for explanation of miRNA biogenesis. Now Drosophila continues to be used in numerous studies aiming to decipher biological roles of individual miRNAs in a living organism. MiRNAs have emerged as an important regulatory class that adjusts gene expression in response to stress; therefore, it is particularly important to elucidate miRNA-based regulatory networks that appear in response to fluctuations in intrinsic and extrinsic environments. This review explores the major advances in understanding condition-dependent roles of miRNAs in adult stem cell biology using the Drosophila ovarian germline stem cell niche community as a model system.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Insect Sci.
    Title
    Current opinion in insect science
    ISBN/ISSN
    2214-5753 2214-5745
    Data From Reference