Dean, D.M., Codd, L.E., Eras, M., Lopez, K., Pham, H., Taylor, D., Abakura, A., Gabriel, Z., Granados, A.J., Litvak-Hinenzon, B., Wen, J., Yturralde, C., Deitcher, D.L. (2026). julius seizure acts within teashirt -expressing neurons to protect Drosophila melanogaster from bang-sensitivity.  MicroPubl Biol 2026(): .

FBrf0265653

Research paper

Loss of function in the Drosophila melanogaster gene julius seizure (jus) causes the fly to have a seizure-like condition known as bang-sensitivity. Here, we characterize the expression patterns of two different jus reporters, a jus -GAL4 construct and a jus protein trap allele, in the central nervous system during the developmental stages that jus expression is required. The majority of cells that expressed the jus -GAL4 construct co-expressed a GAL80 enhancer trap in the homeotic gene teashirt (tsh); expression of jus in this subpopulation was necessary to prevent bang-sensitivity.

PMC13280811 (PMC) (EuropePMC)