FB2026_03 , released September 17, 2026
Experimental tool: Tag:degron(hCDT1-30-120)
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General Information
Symbol
Tag:degron(hCDT1-30-120)
FlyBase ID
FBto0000639
Name
CDT1 30-120 degron sequence
Description
Description

Fragment encoding amino acid residues 30-120 of the Homo sapiens CDT1 gene (HGNC:24576). This fragment contains the Cyclin-binding motif, but not the N-terminal Cul4 E3 ligase-binding sequence or the GMNN binding region of full-length CDT1. If a protein of interest is tagged with this sequence, it is expected to accumulate in the G1 phase only, due to cell-cycle regulated protein degradation (PMID:18267078).

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Related experimental tools
Transgenic Constructs
Tagged with the tool (1)
Transgenic construct(s)
Component allele
Reg. region
Encoded product / tool
Tagged with
Also carries
Stocks
Insertions ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Tag:degron(hCDT1-30-120)
Name Synonyms
CDT1 30-120 degron sequence
Secondary FlyBase IDs
    References (2)