FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-cRaf1.gof}
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General Information
Symbol
P{UAS-cRaf1.gof}
FlyBase ID
FBtp0000374
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\RAF1gof.UAS
Also Known As
UAS-hRafAct
Size
Expression Data
Associated insertion(s)
3 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele Hsap\RAF1gof.UAS
Transgenic product class
gain_of_function_variant
(Brand and Perrimon, 1994)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\RAF1
Description

Gain of function form of Hsap\RAF1 coding sequence is expressed under the influence of UASt regulatory sequences.

(Brand and Perrimon, 1994)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
pP{UAS-cRaf1.gof}
(Brand and Perrimon, 1994)
descendant(s)
Comments

report comment: Human cRaf1, deletion aa 2-334 (constitutively active).

(Brand, 1997.6.30)
Stocks (2)
Stocks containing insertion(s) of this recombinant construct
Bloomington
2074
P{UAS-cRaf1.gof}ra2, y1 w*
Kyoto
106654
P{UAS-cRaf1.gof}ra2, y1 w*
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (13)
Reported As
Symbol Synonym
P{UAS-Hraf.gof}
(FlyBase, 1996-)
P{UAS-cRaf1.gof}
(FlyBase, 1996-)
RAF(gof)
(Roti et al., 2013)
UAS-Rafgof
(Markstein et al., 2014)
UAS-cRaf1gof
(Sinenko and Mathey-Prevot, 2004)
UAS-hRaf
(Lee et al., 2003)
UAS-hRafAct
(Yu et al., 2015)
UAS-hRafact
(Wang et al., 2023)
UAS-hRafgof
(Shun Li et al., 2025)
UAS-human RafgofUAS-ΔcRaf1
(Brand and Perrimon, 1994)
p{UAS-hRafAct}
(Yu et al., 2015)
p{UAS-human RafAct}
(Yu et al., 2013)
Secondary FlyBase IDs
    References (12)