FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-HsapSNCA.A53T}
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General Information
Symbol
P{UAS-Hsap\SNCA.A53T}
FlyBase ID
FBtp0012469
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\SNCAA53T.UAS
Also Known As
UAS-A53T, UAS-αSynA53T, UAS-SNCAA53T, UAS-A53T α-synuclein, UAS-αSynA53T, SNCA.A53T, UAS-h[A53T]αSyn, UAS-α-syn-A53T
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele Hsap\SNCAA53T.UAS
Transgenic product class
missense_variant
(Feany and Bender, 2000)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\SNCA
Description

UASt regulatory sequences drive expression of the mutated A53T form of Hsap\SNCA (which is linked to a familial Parkinson's disease in humans).

(Feany and Bender, 2000)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
8148
w*; P{UAS-Hsap\SNCA.A53T}CG790015.3
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (26)
Reported As
Symbol Synonym
A53T
(Chen and Tully, 2018)
A53T-α-synuclein
(Saridaki et al., 2018)
PUAS-SNCA53T
(Hernández-Vargas et al., 2011)
P{UAS-Hsap\SNCA.A53T}
(Ledahawsky et al., 2022, Jahromi et al., 2015, FlyBase, 1996-)
P{UAS-syn.A53T}
(Botella et al., 2008)
P{UAS-α-synuclein-A53T}
(Navarro et al., 2014)
P{w+mC=UAS-Hsap\SNCA.A53T}
(Saridaki et al., 2018)
P{w[+mC]=UAS-Hsap\SNCA.A53T}
(Dinter et al., 2016)
SNCA p.A53T
(Diaw et al., 2023)
SNCA.A53T
(Golomidov et al., 2022, Golomidov et al., 2020)
UAS-A53T
(Szinyákovics et al., 2023, Jahromi et al., 2015, Jahromi et al., 2015, Cooper et al., 2006, Auluck et al., 2002)
UAS-A53T α-synuclein
(Alexopoulou et al., 2016, Feany and Bender, 2000)
UAS-Hsap SNCAA53T
(Agerschou et al., 2019)
UAS-SNCAA53T
(Xia et al., 2025, Nitta et al., 2023)
UAS-SncaA53T
(Ledahawsky et al., 2022)
UAS-alpha-synucleinA53T
(Ho et al., 2019)
UAS-hSNCAA53T
(Imomnazarov et al., 2024)
UAS-h[A53T]αSyn
(Dhanushkodi et al., 2023, Abul Khair et al., 2018)
UAS-regulated A53T α-syn
(Shaltiel-Karyo et al., 2012)
UAS-synA53T
(Zhu et al., 2016)
UAS-α-Syn-A53T
(Kajtor et al., 2025)
UAS-α-Synuclein.A53T
(Cunningham et al., 2018)
UAS-α-syn-A53T
(Liang et al., 2025)
UAS-αSyn (A53T)
(Varga et al., 2014)
UAS-αSynA53T
(Nitta et al., 2023, Girard et al., 2021, Yan et al., 2019)
UAS-αSynA53T
(Singh et al., 2024, Arsac et al., 2021)
Secondary FlyBase IDs
    References (37)