UASp regulatory sequences drive expression of an activated form of Pvr in which the Pvr extracellular ligand-binding domain has been replaced by the dimerization domain of the bacteriophage λ cI repressor (to induce constitutive dimerization of the encoded protein). A Tag:MYC epitope has been inserted into the BglII site at amino acid residue 785, N-terminal of the transmembrane domain.
UASp regulatory sequences drive expression of an activated form of Pvr in which the Pvr extracellular ligand-binding domain has been replaced by the dimerization domain of the bacteriophage λ cI repressor (to induce constitutive dimerization of the encoded protein). A Tag:MYC epitope has been inserted into the BglII site at amino acid residue 785, N-terminal of the transmembrane domain.