FB2026_03 , released September 17, 2026
Recombinant Construct: P{αTub67C-Btk.SH3.R238K.GFP}
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General Information
Symbol
P{αTub67C-Btk.SH3.R238K.GFP}
FlyBase ID
FBtp0019215
Feature type
transgenic_transposable_element
Component Allele(s)
BtkSH3.SH2.R238K.αTub67C.mGFP6
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele BtkSH3.SH2.R238K.αTub67C.mGFP6
Transgenic product class
inframe_deletion
(Lu et al., 2004)
missense_variant
(Lu et al., 2004)
Component
Use(s)
Regulatory region(s)
αTub67C
Encoded product / tool
Btk
Tagged with
mGFP6
Description

The αTub67C promoter drives expression of the Btk SH3 and SH2 domains, in which a key Arg residue of the SH2 domain has been mutated to Lys (mutation location corresponds to codon 238 of the type 1 isoform and codon 436 of the type 2 isoform). The coding sequence is tagged at the C-terminal end with mGFP6.

(Lu et al., 2004)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{αTub67C-Btk.SH3.R238K.GFP}
(FlyBase, 1996-)
P{αTub67C-Btk29A.SH3.R238K.GFP}
(FlyBase, 1996-)
SH3R238K
(Lu et al., 2004)
Secondary FlyBase IDs
    References (4)