FlyBase Recombinant Construct Report: P{UAS-TDP-43.M337V.Myc}

General Information

Symbol

P{UAS-TDP-43.M337V.Myc}

FlyBase ID

FBtp0068034

Feature type

transgenic_transposable_element

Component Allele(s)

Hsap\TARDBP^{M337V.UAS.Tag:MYC}

Also Known As

UAS-TDP-43 M337V, TDP-43^M337V, UAS-hTDP-43^M337V, UAS-TDP-43-M337V

Size

Expression Data

Associated insertion(s)

1 available

Molecular map

Description and Uses

Construct components

Component allele Hsap\TARDBP^{M337V.UAS.Tag:MYC}

Transgenic product class

missense_variant

(Ritson et al., 2010)

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\TARDBP

Tagged with

Tag:MYC

epitope tag

Description

UASt regulatory sequences drive expression of Hsap\TARDBP coding sequences which carry the ALS disease-causing M337V mutation. The protein is tagged with Tag:MYC.

(Ritson et al., 2010)

Sequence Data

Sequence (FB)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA Sequence

Extent

Segments and Size

Total Size

Left end

Right end

Segments

Num

Orientation

Symbol

Reference

Phenotypic Data

Component Allele

Phenotypic Data

Hsap\TARDBP^{M337V.UAS.Tag:MYC}

Phenotypic Class Phenotype Manifest In Detailed Description

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Progenitors and Descendants

progenitor(s)

descendant(s)

Comments

Stocks (0)

Stocks containing insertion(s) of this recombinant construct

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (18)

Reported As

Symbol Synonym

ALS

(Ritson et al., 2010)

P{UAS-TDP-43.M337V.Myc}

(Xiang et al., 2025, Zhang et al., 2020, FlyBase, 1996-)

P{UAS-TDP-43.M337V}

(FlyBase, 1992-)

TDP-43 M337V

(Crippa et al., 2016)

TDP-43(M337V)

(Ritson et al., 2010)

TDP-43^M337V

(Huber et al., 2023, Kim et al., 2018)

TDP-M337V

(Fortuna et al., 2021)

UAS-TDP-43 M337V

(Casci et al., 2019, Lanson et al., 2011)

UAS-TDP-43 M337V-Myc

(Uechi et al., 2018)

UAS-TDP-43-M337V

(Pandey et al., 2025, Huelsmeier et al., 2021)

UAS-TDP-43-hM337V

(Markmiller et al., 2018)

UAS-TDP-43^M337V

(Xiang et al., 2025)

UAS-hTDP-43 M337V

(Pandey et al., 2025)

UAS-hTDP-43-M337V

(Periz et al., 2015)

UAS-hTDP-43^M337V

(Khalil et al., 2022, Kankel et al., 2020)

UAS-hTDP43^M337V

(Ho et al., 2024)

UAS-myc-TDP-43 M337V

(He et al., 2014)

UASt-TDP43-M337

(Glineburg et al., 2024)

Secondary FlyBase IDs

References (23)

Report Sections

Open Close