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General Information
Symbol
P{UAS-IP3-sponge.m30}
FlyBase ID
FBtp0068098
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Location-dependent role
Description
CV term
Qualifiers and info
Reference
transposon
Construct components
Product class / Tool use(s)
Description

UASt regulatory sequences drive expression of an inositol 1, 4, 5-trisphosphate (IP[[3]]) "sponge" which retains the ability to bind IP[[3]] without exerting any physiological activity, thus titrating cellular IP[[3]]. The sponge sequence consists of a 380 amino acid peptide derived from the ligand binding site of the Mmus\Itpr1 gene which has been mutated to carry the amino acid replacement K508A.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Features
CV term
Qualifiers and info
Reference
Component Alleles
Molecular data

UASt regulatory sequences drive expression of an inositol 1, 4, 5-trisphosphate (IP[[3]]) "sponge" which retains the ability to bind IP[[3]] without exerting any physiological activity, thus titrating cellular IP[[3]]. The sponge sequence consists of a 380 amino acid peptide derived from the ligand binding site of the Mmus\Itpr1 gene which has been mutated to carry the amino acid replacement K508A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
P{UAS-IP3-sponge.m30}
P{UAS-Mmus\Itpr1.K508A}
UAS-IP3 sponge m30
Secondary FlyBase IDs
    References (3)