FB2026_02 , released June 18, 2026
Recombinant Construct: M{3xHisGU.ΔH3.2}
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General Information
Symbol
M{3xHisGU.ΔH3.2}
FlyBase ID
FBtp0082369
Feature type
transgenic_transposable_element
Component Allele(s)
His1HisGU.wt
His2AHisGU.wt
His2BHisGU.wt
His3GU.ΔH3.2
His4HisGU.wt
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele His1HisGU.wt
Transgenic product class
wild_type
(Günesdogan et al., 2010)
Component
Use(s)
Regulatory region(s)
His1
Encoded product / tool
His1
Description

Wild-type His1 gene in the context of a histone gene repeat unit.

(Günesdogan et al., 2010)
Component allele His2AHisGU.wt
Transgenic product class
wild_type
(Günesdogan et al., 2010)
Component
Use(s)
Regulatory region(s)
His2A
Encoded product / tool
His2A
Description

Wild-type His2A gene in the context of a histone gene repeat unit.

(Günesdogan et al., 2010)
Component allele His3GU.ΔH3.2
Transgenic product class
frameshift_variant
(Hödl and Basler, 2012)
start_lost
(Hödl and Basler, 2012)
Component
Use(s)
Regulatory region(s)
His3
Encoded product / tool
His3
Description

The ATG start codon has been mutated to AGA, inserting a SacI restriction site, and a 1bp deletion has been introduced at codon 90 to destroy the second in-frame ATG and shift the succeeding reading frame.

(Hödl and Basler, 2012)
Component allele His2BHisGU.wt
Transgenic product class
wild_type
(Günesdogan et al., 2010)
Component
Use(s)
Regulatory region(s)
His2B
Encoded product / tool
His2B
Description

Wild-type His2B gene in the context of a histone gene repeat unit.

(Günesdogan et al., 2010)
Component allele His4HisGU.wt
Transgenic product class
wild_type
(Günesdogan et al., 2010)
Component
Use(s)
Regulatory region(s)
His4
Encoded product / tool
His4
Description

Wild-type His4 gene in the context of a histone gene repeat unit.

(Günesdogan et al., 2010)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
M{3xHisGU.wt}
(Hödl and Basler, 2012)
descendant(s)
Comments

The ATG start codon in each copy of His3 has been mutated to AGA, inserting a SacI restriction site, and a 1bp deletion has been introduced at codon 90 to destroy the second in-frame ATG and shift the succeeding reading frame.

(Hödl and Basler, 2012)

Four copies of M{3xHisGU.ΔH3.2} rescue the formation of homozygous Df(2L)BSC104 clones in the wing disc, although they are severely growth impaired compared to their wild-type twin spots.

(Hödl and Basler, 2012)

Two copies of M{3xHisGU.ΔH3.2} do not rescue the formation of homozygous Df(2L)BSC104 clones in the wing disc in a His3.3AKO His3.3BKO background.

(Hödl and Basler, 2012)
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
M{3xHisGU.ΔH3.2}
(FlyBase, 1996-)
ΔH3
(Hödl and Basler, 2012)
ΔH3.2
(Hödl and Basler, 2012)
Secondary FlyBase IDs
    References (3)